Autoimmun májbetegségek átfedo (overlap) szindrómáinak áttekintése. A felismerés és a kezelés nehézségei

Translated title of the contribution: Review of overlap syndromes of autoimmune liver diseases. Difficulties in the diagnosis and treatment

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Overlap syndromes are biochemical, serological, histological and radiological overlaps across the classic autoimmune liver diseases in the presence of autoimmun hepatitis and primary biliary cirrhosis or primary sclerosing cholangitis. The exact prevalence of the disease is not known, but it may vary between 5% and 20%. Because it has no generally accepted diagnostic criteria, clinical signs, biochemical, serological, radiological and histological findings are evaluated together. Treatment depends on the predominant feature of the overlap syndrome; ursodeoxycholic acid and/or immunsuppressive (corticosteroid) treatment are used, based on observations from retrospective, non-randomized studies. Orv. Hetil., 2013, 154, 923-929.

Original languageHungarian
Pages (from-to)923-929
Number of pages7
JournalOrvosi Hetilap
Volume154
Issue number24
DOIs
Publication statusPublished - Jun 1 2013

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Autoimmune Diseases
Liver Diseases
Ursodeoxycholic Acid
Sclerosing Cholangitis
Biliary Liver Cirrhosis
Hepatitis
Adrenal Cortex Hormones
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Autoimmun m{\'a}jbetegs{\'e}gek {\'a}tfedo (overlap) szindr{\'o}m{\'a}inak {\'a}ttekint{\'e}se. A felismer{\'e}s {\'e}s a kezel{\'e}s neh{\'e}zs{\'e}gei",
abstract = "Overlap syndromes are biochemical, serological, histological and radiological overlaps across the classic autoimmune liver diseases in the presence of autoimmun hepatitis and primary biliary cirrhosis or primary sclerosing cholangitis. The exact prevalence of the disease is not known, but it may vary between 5{\%} and 20{\%}. Because it has no generally accepted diagnostic criteria, clinical signs, biochemical, serological, radiological and histological findings are evaluated together. Treatment depends on the predominant feature of the overlap syndrome; ursodeoxycholic acid and/or immunsuppressive (corticosteroid) treatment are used, based on observations from retrospective, non-randomized studies. Orv. Hetil., 2013, 154, 923-929.",
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