Reversal of isoproterenol-induced calorigenic action in the heart during myocardial ischemia.

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Abstract

With the aid of infrared thermography, a powerful new tool for studying the biological state of cardiac regulatory mechanisms, the reversal of the isoproterenol-induced calorigenic action in the in situ dog heart was demonstrated after establishing acute myocardial ischemia. The thermographic manifestations indicated a modified activity pattern of the cardiac (coronary) beta-mechanism with a preserved sensitivity to its specific pharmacologic blockade. Results provide new evidence of the transformation (plasticity) of adrenoceptor qualities under pathologic circumstances.

Original languageEnglish
Pages (from-to)31-38
Number of pages8
JournalActa biologica Hungarica
Volume39
Issue number1
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Neurology

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