With the aid of infrared thermography, a powerful new tool for studying the biological state of cardiac regulatory mechanisms, the reversal of the isoproterenol-induced calorigenic action in the in situ dog heart was demonstrated after establishing acute myocardial ischemia. The thermographic manifestations indicated a modified activity pattern of the cardiac (coronary) beta-mechanism with a preserved sensitivity to its specific pharmacologic blockade. Results provide new evidence of the transformation (plasticity) of adrenoceptor qualities under pathologic circumstances.
|Number of pages||8|
|Journal||Acta biologica Hungarica|
|Publication status||Published - 1988|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Environmental Science(all)