Retinal microcirculation correlates with ocular wall thickness, axial eye length, and refraction in glaucoma patients

J. Németh, Georg Michelson, Joanna Harazny

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Purpose: To examine the correlations of refraction, axial eye length, and posterior eye wall thickness with retinal microcirculation. Patients and Methods: In a prospective study, 25 patients with primary open-angle glaucoma, 12 patients with ocular hypertension, and 12 healthy subjects were examined; only one eye of each participant was considered in the analysis. Posterior eye wall thickness and axial eye length were measured with standardized A-scan ultrasonography. Retinal microcirculation temporal to the optic disc was determined by a scanning laser Doppler flowmeter using automatic full-field perfusion image analyzer software. Results: In glaucoma patients, temporal retinal mean flow exhibited significant correlation to the eye wall thickness (r = 0.470, P = 0.042), axial eye length (r = -0.570, P = 0.011), and refraction of the eye (r = 0.520, P = 0.022). In glaucomatous eyes, the temporal retinal mean flow was significantly lower than in healthy subjects or in ocular hypertensive patients (P = 0.01). Conclusions: Myopic eyes have longer axial eye length and thinner ocular wall than emmetropic eyes. In glaucoma patients, the longer the axial eye length and the thinner the ocular wall, the more reduced the retinal microcirculation. The reduced microcirculation found in myopic glaucomatous eyes might contribute to the development of glaucomatous damage in these eyes.

Original languageEnglish
Pages (from-to)390-395
Number of pages6
JournalJournal of Glaucoma
Volume10
Issue number5
Publication statusPublished - 2001

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Eye Axial Length
Microcirculation
Glaucoma
Healthy Volunteers
Flowmeters
Ocular Hypertension
Optic Disk

Keywords

  • Glaucoma
  • Myopia
  • Retinal microcirculation
  • Ultrasound biometry

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Retinal microcirculation correlates with ocular wall thickness, axial eye length, and refraction in glaucoma patients. / Németh, J.; Michelson, Georg; Harazny, Joanna.

In: Journal of Glaucoma, Vol. 10, No. 5, 2001, p. 390-395.

Research output: Contribution to journalArticle

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