The retention of 19 solutes markedly differing in their physicochemical characteristics was determined on titanium dioxide and polyethylene-coated titanium dioxide columns in water and water-methanol eluent mixtures. Principal component analysis was used for the elucidation of the relationship between retention behavior and physicochemical parameters. Polyethylene-coated titanium dioxide showed stronger retention than titanium dioxide did, proving the retention increasing effect of polyethylene coating. Retention parameters formed a loose cluster with the excess molar refraction and the effective hydrogen bond acidity of solutes on the two-dimensional nonlinear map of principal component loadings, indicating the involvement of steric conditions and electronic interactions in the retention.
|Number of pages||11|
|Journal||Journal of Liquid Chromatography and Related Technologies|
|Publication status||Published - Nov 1997|
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmaceutical Science
- Clinical Biochemistry