Retention characteristics of a (2,3,6-tri-O-methyl)-beta-cyclodextrin coated capillary column

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The separation efficiency of a glass capillary column coated with (2,3,6-tri-O-methyl)-beta-cyclodextrin was determined at the temperature and carrier gas flow rate ranges of 105-165°C and 0.5-1.5 ml/min, respectively, using (+) and (-) g-lactones as test compounds. Stepwise regression analysis was employed for the elucidation of the temperature and flow rate on the efficiency of separation. The column separated the enantiomers at each temperature and flow rate proving the excellent separation power of the cyclodextrin coating. The differences of the retention times of isomers and the sum of their peak widths depended on the logarithm and on the reciprocal value of temperature: the effect of flow rate was negligible. The significant impact of the reciprocal value of temperature can be explained by the inclusion complex formation between cyclodextrin and g-lactone isomers.

Original languageEnglish
Pages (from-to)145-153
Number of pages9
JournalAnalytical Letters
Volume34
Issue number1
DOIs
Publication statusPublished - 2001

Fingerprint

tri-O-methyl-beta-cyclodextrin
Cyclodextrins
Temperature
Flow rate
Lactones
Isomers
Enantiomers
Regression analysis
Glass
Flow of gases
Gases
Regression Analysis
Coatings

Keywords

  • (2,3,6-tri-o-methyl)-beta-cyclodextrin
  • g-lactone-isomers
  • Optimization

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

Cite this

Retention characteristics of a (2,3,6-tri-O-methyl)-beta-cyclodextrin coated capillary column. / Cserháti, T.; Forgács, E.

In: Analytical Letters, Vol. 34, No. 1, 2001, p. 145-153.

Research output: Contribution to journalArticle

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