Retention behaviour of some ring-substituted phenol derivatives on a porous graphitized carbon column

E. Forgács, T. Cserháti, Klára Valkó

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The retentions of 24 ring-substituted phenol derivatives were determined on a graphitized carbon column using unbuffered acetonitrile-water and methanol-water eluent mixtures at various organic phase concentrations. Principal component analysis calculated from both the correlation and covariance matrices was used to detect the similarities and dissimilarities between the retention behaviours of phenol derivatives. Each phenol derivative showed narrow and symmetrical peaks in each eluent. The high percentage of variance explained in the first principal component suggests that the eluents have common elution characteristics; however, according to the second principal component they showed slightly different selectivities. Calculations demonstrated that the number and not the type of substituents exerts the highest impact on the retention. Both calculation methods (based on correlation and covariance matrices) gave similar results.

Original languageEnglish
Pages (from-to)75-83
Number of pages9
JournalJournal of Chromatography A
Volume592
Issue number1-2
DOIs
Publication statusPublished - Feb 21 1992

Fingerprint

Phenol
Carbon
Covariance matrix
Derivatives
Water
Principal Component Analysis
Principal component analysis
Methanol

ASJC Scopus subject areas

  • Analytical Chemistry
  • Clinical Biochemistry
  • Molecular Medicine

Cite this

Retention behaviour of some ring-substituted phenol derivatives on a porous graphitized carbon column. / Forgács, E.; Cserháti, T.; Valkó, Klára.

In: Journal of Chromatography A, Vol. 592, No. 1-2, 21.02.1992, p. 75-83.

Research output: Contribution to journalArticle

@article{4f2a1f779eb24964a2dd4103f9e7f15f,
title = "Retention behaviour of some ring-substituted phenol derivatives on a porous graphitized carbon column",
abstract = "The retentions of 24 ring-substituted phenol derivatives were determined on a graphitized carbon column using unbuffered acetonitrile-water and methanol-water eluent mixtures at various organic phase concentrations. Principal component analysis calculated from both the correlation and covariance matrices was used to detect the similarities and dissimilarities between the retention behaviours of phenol derivatives. Each phenol derivative showed narrow and symmetrical peaks in each eluent. The high percentage of variance explained in the first principal component suggests that the eluents have common elution characteristics; however, according to the second principal component they showed slightly different selectivities. Calculations demonstrated that the number and not the type of substituents exerts the highest impact on the retention. Both calculation methods (based on correlation and covariance matrices) gave similar results.",
author = "E. Forg{\'a}cs and T. Cserh{\'a}ti and Kl{\'a}ra Valk{\'o}",
year = "1992",
month = "2",
day = "21",
doi = "10.1016/0021-9673(92)85075-5",
language = "English",
volume = "592",
pages = "75--83",
journal = "Journal of Chromatography",
issn = "0021-9673",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Retention behaviour of some ring-substituted phenol derivatives on a porous graphitized carbon column

AU - Forgács, E.

AU - Cserháti, T.

AU - Valkó, Klára

PY - 1992/2/21

Y1 - 1992/2/21

N2 - The retentions of 24 ring-substituted phenol derivatives were determined on a graphitized carbon column using unbuffered acetonitrile-water and methanol-water eluent mixtures at various organic phase concentrations. Principal component analysis calculated from both the correlation and covariance matrices was used to detect the similarities and dissimilarities between the retention behaviours of phenol derivatives. Each phenol derivative showed narrow and symmetrical peaks in each eluent. The high percentage of variance explained in the first principal component suggests that the eluents have common elution characteristics; however, according to the second principal component they showed slightly different selectivities. Calculations demonstrated that the number and not the type of substituents exerts the highest impact on the retention. Both calculation methods (based on correlation and covariance matrices) gave similar results.

AB - The retentions of 24 ring-substituted phenol derivatives were determined on a graphitized carbon column using unbuffered acetonitrile-water and methanol-water eluent mixtures at various organic phase concentrations. Principal component analysis calculated from both the correlation and covariance matrices was used to detect the similarities and dissimilarities between the retention behaviours of phenol derivatives. Each phenol derivative showed narrow and symmetrical peaks in each eluent. The high percentage of variance explained in the first principal component suggests that the eluents have common elution characteristics; however, according to the second principal component they showed slightly different selectivities. Calculations demonstrated that the number and not the type of substituents exerts the highest impact on the retention. Both calculation methods (based on correlation and covariance matrices) gave similar results.

UR - http://www.scopus.com/inward/record.url?scp=0026599450&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026599450&partnerID=8YFLogxK

U2 - 10.1016/0021-9673(92)85075-5

DO - 10.1016/0021-9673(92)85075-5

M3 - Article

AN - SCOPUS:0026599450

VL - 592

SP - 75

EP - 83

JO - Journal of Chromatography

JF - Journal of Chromatography

SN - 0021-9673

IS - 1-2

ER -