The authors report on the outcome of liver transplantations performed due to liver tumours. Between the Ist January,1995 and 30th September, 1998, 61 orthotopic liver transplantations were performed, 9 of them due to liver tumours. Patients were divided into two groups (1st group: primary hepatic cell carcinoma, and 2nd group: metastases of low malignancy tumours). Retrospective data analysis was made to evaluate and compare the clinical course and prognosis. Six patients were in the 1 st, while 3 were in the 2nd group (liver metastases of carcinoid, leiomyosarcoma and stroma tumour). The mortality in the I st group was 66% within 6 months, and 33% in the 2nd group. The only patient who died in the 2nd group bad chronic irreversible graft rejection and was tumour and metastasis free at the time of death, while one of the patients who is still alive (for over 2years now) had local recurrence and bone metastases. As a summary, our data are similar to those found in the literature, however, the 1 year survival of the primary hepatic tumours (16.6%, 1 patient) is worse. According to our results as well as the literary data, liver transplantations of highly differentiated primary hepatic turnouts ( minuit cancer) and liver metastases of low malignancy (endocrine, mesenchymal) tumours have acceptable outcome.
|Translated title of the contribution||Results of orthotopic liver transplantations due to liver tumours in Hungary|
|Number of pages||6|
|Publication status||Published - Dec 1 1999|
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