The rationale and results of using epididymal and testicular spermatozoa with intracytoplasmic sperm injection (ICSI) for azoospermic patients are reviewed. A total of 128 consecutive ICSI/MESA cycles and a total of 120 consecutive ICSI/TESE cycles were performed up to December 1994. The two-pronuclei fertilization rate per intact oocyte (observed after the injection) was 58% and 60%, respectively, when epididymal and testicular spermatozoa were used. The embryo transfer rate was similar for the two procedures (91% after ICSI/MESA and 90% after ICSI/TESE). Fifty women became pregnant (positive HCG) when epididymal spermatozoa were used (39% per cycle and 43% per embryo transfer). Similar results were observed in the group of patients undergoing ICSI using testicular spermatozoa (36% per cycle and 40% per embryo transfer). These results are comparable to those obtained when ejaculated spermatozoa are used.
|Number of pages||5|
|Issue number||SUPPL. 1|
|Publication status||Published - Dec 1 1996|
- intracytoplasmic sperm injection (ICSI)
- microsurgical epididymal sperm aspiration (MESA)
- testicular sperm extraction (TESE)
ASJC Scopus subject areas