Results of contact beta-irradiation of choroidal melanomas.

J. Damjanovich, A. Berta, L. Vezendi

Research output: Contribution to journalArticle

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Abstract

Between the end of 1986 and the end of October 1996 81 patients suffering from choroidal melanoma were irradiated at the Department of Ophthalmology University Medical School of Debrecen. The irradiations were performed with Ruthenium-106 beta ray emitting scleral plaques (ophthalmic applicators). The radioactive plaques were implanted surgically, fixed by episcleral sutures onto the sclera covering the base of the tumour, and removed by another operation when sufficient time for irradiation had elapsed. For the treatment of tumours in the vicinity of the optic nerve special plaques were used with a notch for the nerve. Precise localisation of the tumours was established by intraoperative ultrasonography and transillumination. The mean follow up period was 3.5 years after the irradiation. Tumour regression was recorded by fluorescein angiography, ultrasonography and fundus photography. In 75 cases (92.5%) the treatment was successful. Additional laser photocoagulation was performed after irradiation in 26 cases. The irradiation by Ruthenium-106 scleral plaques of choroidal melanomas proved to be an effective treatment in cases of small and medium sized choroidal melanomas in our practice and the results are similar to those of the largest radiotherapy centers of Europe.

Original languageEnglish
Pages (from-to)67-68
Number of pages2
JournalActa Chirurgica Hungarica
Volume36
Issue number1-4
Publication statusPublished - 1997

Fingerprint

Melanoma
Ruthenium
Ultrasonography
Neoplasms
Beta Particles
Transillumination
Sclera
Fluorescein Angiography
Light Coagulation
Photography
Ophthalmology
Optic Nerve
Medical Schools
Sutures
Lasers
Radiotherapy
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Results of contact beta-irradiation of choroidal melanomas. / Damjanovich, J.; Berta, A.; Vezendi, L.

In: Acta Chirurgica Hungarica, Vol. 36, No. 1-4, 1997, p. 67-68.

Research output: Contribution to journalArticle

Damjanovich, J, Berta, A & Vezendi, L 1997, 'Results of contact beta-irradiation of choroidal melanomas.', Acta Chirurgica Hungarica, vol. 36, no. 1-4, pp. 67-68.
Damjanovich, J. ; Berta, A. ; Vezendi, L. / Results of contact beta-irradiation of choroidal melanomas. In: Acta Chirurgica Hungarica. 1997 ; Vol. 36, No. 1-4. pp. 67-68.
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