Compared with control animals without hormone action, newborn rats treated with thyroid stimulating hormone (TSH) developed more exocytotic vesicles and enlarged endoplasmic reticulum filled with products in the thyroid gland up to the first postnatal week. A single administration of the hormone in newborn rats (imprinting) resulted in a long-lasting effect on the functioning of the cells of the thyroid gland. Single hormone action in postnatal 1-week-old animals provoked the discharge of products from the cells into the follicles of the thyroid gland with a concurrent endocytosis within 5 min after treatment. A similar but more vigorous effect was demonstrable in animals treated with TSH in newborn (hormonal imprinting) and postnatal 1-week-old conditions. Such events were accompanied by the death of certain cells while others developed myelin-like structures and showed signs of folliculogenesis in the cytoplasm.
|Number of pages||9|
|Publication status||Published - 1993|
ASJC Scopus subject areas
- Aquatic Science
- Cell Biology