Respiratory mechanical impedance in the rat.

Z. Hantos, B. Daróczy, B. Suki, S. Nagy, L. A. Debreczeni

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The forced oscillatory impedance of the total respiratory system (Zrs) was measured in seven anaesthetized, paralysed rats weighing 351 +/- 55 g. Tracheotomy was performed, and the animals were placed in the supine position in a body box. Pseudo-random pressure variations between 0.5 and 10 Hz were applied around the chest. Central airflow was measured with a heated screen pneumotachograph. Total respiratory resistance (Rrs) and elastance (Ers), corrected for the impedance of the tracheal cannula, were markedly frequency-dependent: Rrs fell from 37.3 +/- 19.1 kPa.l-1.s at 0.5 Hz to 17.6 +/- 4.4 at 2 Hz and 10.3 +/- 3.3 at 10 Hz; the corresponding Ers values were 453 +/- 14, 594 +/- 90 and 713 +/- 104 kPa.l-1, respectively. This indicates that in the frequency range encompassing spontaneous breathing rates the classical resistance-intertance-compliance model provides an inadequate description of the respiratory mechanics in the rat.

Original languageEnglish
Pages (from-to)289-296
Number of pages8
JournalActa physiologica Hungarica
Volume70
Issue number2-3
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Physiology (medical)

Fingerprint Dive into the research topics of 'Respiratory mechanical impedance in the rat.'. Together they form a unique fingerprint.

  • Cite this

    Hantos, Z., Daróczy, B., Suki, B., Nagy, S., & Debreczeni, L. A. (1987). Respiratory mechanical impedance in the rat. Acta physiologica Hungarica, 70(2-3), 289-296.