Residue formation of fumonisin B1 in porcine tissues

Karsten Meyer, K. Mohr, J. Bauer, P. Horn, M. Kovács

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

The residues derived from the uptake of fumonisin B1, a toxic metabolite of Fusarium verticillioides frequently occurring in corn and corn products, were determined in growing pigs. After oral administration of 100 mg FB1/animal/day for 5-11 days, serum, bile, lung, liver, kidney, brain, spleen, pancreas, heart, muscle, eye, and fat samples were collected immediately and analysed by LC-MS. The highest values were measured in kidney (833 ± 1329 μg kg-1, mean ± SD ), liver (231 ± 163 μg kg-1 ), lung ( 170 ± 311 μg kg-1 ) and spleen (854 ± 2212 μg kg-1 ). Muscle contained 26 ± 41 μg kg-1, while in fat only 2 ± 3 μg kg-1 were traceable. Despite the potential accumulation over extended feeding periods as well as the large variations in the residue formation of FB1, a carry-over in edible tissues from swine was considered not to be of toxicological relevance.

Original languageEnglish
Pages (from-to)639-647
Number of pages9
JournalFood Additives and Contaminants
Volume20
Issue number7
DOIs
Publication statusPublished - Jul 1 2003

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fumonisin B1
Liver
Zea mays
Muscle
spleen
Swine
Spleen
Fats
lungs
kidneys
corn products
Tissue
Kidney
Lung
muscles
liver
swine
Poisons
Fusarium
lipids

Keywords

  • Consumer health
  • Fumonisin
  • LC-MS
  • Mycotoxin
  • Pig
  • Residues

ASJC Scopus subject areas

  • Food Science
  • Chemistry (miscellaneous)
  • Toxicology
  • Health, Toxicology and Mutagenesis

Cite this

Residue formation of fumonisin B1 in porcine tissues. / Meyer, Karsten; Mohr, K.; Bauer, J.; Horn, P.; Kovács, M.

In: Food Additives and Contaminants, Vol. 20, No. 7, 01.07.2003, p. 639-647.

Research output: Contribution to journalArticle

Meyer, Karsten ; Mohr, K. ; Bauer, J. ; Horn, P. ; Kovács, M. / Residue formation of fumonisin B1 in porcine tissues. In: Food Additives and Contaminants. 2003 ; Vol. 20, No. 7. pp. 639-647.
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