Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: Current status in 37 ESC countries

Steen D. Kristensen, Kristina G. Laut, Jean Fajadet, Zuzana Kaifoszova, Petr Kala, Carlo Di Mario, William Wijns, Peter Clemmensen, Vaja Agladze, Loizos Antoniades, Khalid F. Alhabib, Menko Jan De Boer, Marc J. Claeys, Dan Deleanu, Dariusz Dudek, Andrejs Erglis, Martine Gilard, Omer Goktekin, Giulio Guagliumi, Thorarinn GudnasonKim Wadt Hansen, Kurt Huber, Stefan James, Tomáš Janota, Siobhan Jennings, Olli Kajander, John Kanakakis, Kiril K. Karamfiloff, Sasko Kedev, Ran Kornowski, Peter F. Ludman, B. Merkely, Davor Milicic, Ruslan Najafov, Francesca A. Nicolini, Marko Noč, Miodrag Ostojic, Hélder Pereira, Dragana Radovanovic, Manel Sabaté, Mohamed Sobhy, Maxim Sokolov, Martin Studencan, Ibrahim Terzic, Steffen Wahler, Petr Widimsky

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

Aims: Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries. Methods and results A cross-sectional descriptive study based on aggregated country-level data on the use of reperfusion therapy in patients admitted with STEMI during 2010 or 2011. Thirty-seven ESC countries were able to provide data from existing national or regional registries. In countries where no such registries exist, data were based on best expert estimates. Data were collected on the use of STEMI reperfusion treatment and mortality, the numbers of cardiologists, and the availability of PPCI facilities in each country. Our survey provides a brief data summary of the degree of variation in reperfusion therapy across Europe. The number of PPCI procedures varied between countries, ranging from 23 to 884 per million inhabitants. Primary percutaneous coronary intervention and thrombolysis were the dominant reperfusion strategy in 33 and 4 countries, respectively. The mean population served by a single PPCI centre with a 24-h service 7 days a week ranged from 31 300 inhabitants per centre to 6 533 000 inhabitants per centre. Twenty-seven of the total 37 countries participated in a former survey from 2007, and major increases in PPCI utilization were observed in 13 of these countries. Conclusion Large variations in reperfusion treatment are still present across Europe. Countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusion therapy. Implementation of the best reperfusion therapy as recommended in the guidelines should be encouraged. All rights reserved.

Original languageEnglish
Pages (from-to)1957-1970
Number of pages14
JournalEuropean Heart Journal
Volume35
Issue number29
DOIs
Publication statusPublished - Aug 1 2014

Fingerprint

Cardiology
Reperfusion
Percutaneous Coronary Intervention
Therapeutics
Registries
Eastern Europe
Myocardial Reperfusion
ST Elevation Myocardial Infarction
Cross-Sectional Studies
Guidelines
Mortality
Population

Keywords

  • Europe
  • Primary percutaneous coronary intervention
  • STEMI
  • Treatment variation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

Cite this

Kristensen, S. D., Laut, K. G., Fajadet, J., Kaifoszova, Z., Kala, P., Di Mario, C., ... Widimsky, P. (2014). Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: Current status in 37 ESC countries. European Heart Journal, 35(29), 1957-1970. https://doi.org/10.1093/eurheartj/eht529

Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011 : Current status in 37 ESC countries. / Kristensen, Steen D.; Laut, Kristina G.; Fajadet, Jean; Kaifoszova, Zuzana; Kala, Petr; Di Mario, Carlo; Wijns, William; Clemmensen, Peter; Agladze, Vaja; Antoniades, Loizos; Alhabib, Khalid F.; De Boer, Menko Jan; Claeys, Marc J.; Deleanu, Dan; Dudek, Dariusz; Erglis, Andrejs; Gilard, Martine; Goktekin, Omer; Guagliumi, Giulio; Gudnason, Thorarinn; Hansen, Kim Wadt; Huber, Kurt; James, Stefan; Janota, Tomáš; Jennings, Siobhan; Kajander, Olli; Kanakakis, John; Karamfiloff, Kiril K.; Kedev, Sasko; Kornowski, Ran; Ludman, Peter F.; Merkely, B.; Milicic, Davor; Najafov, Ruslan; Nicolini, Francesca A.; Noč, Marko; Ostojic, Miodrag; Pereira, Hélder; Radovanovic, Dragana; Sabaté, Manel; Sobhy, Mohamed; Sokolov, Maxim; Studencan, Martin; Terzic, Ibrahim; Wahler, Steffen; Widimsky, Petr.

In: European Heart Journal, Vol. 35, No. 29, 01.08.2014, p. 1957-1970.

Research output: Contribution to journalArticle

Kristensen, SD, Laut, KG, Fajadet, J, Kaifoszova, Z, Kala, P, Di Mario, C, Wijns, W, Clemmensen, P, Agladze, V, Antoniades, L, Alhabib, KF, De Boer, MJ, Claeys, MJ, Deleanu, D, Dudek, D, Erglis, A, Gilard, M, Goktekin, O, Guagliumi, G, Gudnason, T, Hansen, KW, Huber, K, James, S, Janota, T, Jennings, S, Kajander, O, Kanakakis, J, Karamfiloff, KK, Kedev, S, Kornowski, R, Ludman, PF, Merkely, B, Milicic, D, Najafov, R, Nicolini, FA, Noč, M, Ostojic, M, Pereira, H, Radovanovic, D, Sabaté, M, Sobhy, M, Sokolov, M, Studencan, M, Terzic, I, Wahler, S & Widimsky, P 2014, 'Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: Current status in 37 ESC countries', European Heart Journal, vol. 35, no. 29, pp. 1957-1970. https://doi.org/10.1093/eurheartj/eht529
Kristensen, Steen D. ; Laut, Kristina G. ; Fajadet, Jean ; Kaifoszova, Zuzana ; Kala, Petr ; Di Mario, Carlo ; Wijns, William ; Clemmensen, Peter ; Agladze, Vaja ; Antoniades, Loizos ; Alhabib, Khalid F. ; De Boer, Menko Jan ; Claeys, Marc J. ; Deleanu, Dan ; Dudek, Dariusz ; Erglis, Andrejs ; Gilard, Martine ; Goktekin, Omer ; Guagliumi, Giulio ; Gudnason, Thorarinn ; Hansen, Kim Wadt ; Huber, Kurt ; James, Stefan ; Janota, Tomáš ; Jennings, Siobhan ; Kajander, Olli ; Kanakakis, John ; Karamfiloff, Kiril K. ; Kedev, Sasko ; Kornowski, Ran ; Ludman, Peter F. ; Merkely, B. ; Milicic, Davor ; Najafov, Ruslan ; Nicolini, Francesca A. ; Noč, Marko ; Ostojic, Miodrag ; Pereira, Hélder ; Radovanovic, Dragana ; Sabaté, Manel ; Sobhy, Mohamed ; Sokolov, Maxim ; Studencan, Martin ; Terzic, Ibrahim ; Wahler, Steffen ; Widimsky, Petr. / Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011 : Current status in 37 ESC countries. In: European Heart Journal. 2014 ; Vol. 35, No. 29. pp. 1957-1970.
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T1 - Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011

T2 - Current status in 37 ESC countries

AU - Kristensen, Steen D.

AU - Laut, Kristina G.

AU - Fajadet, Jean

AU - Kaifoszova, Zuzana

AU - Kala, Petr

AU - Di Mario, Carlo

AU - Wijns, William

AU - Clemmensen, Peter

AU - Agladze, Vaja

AU - Antoniades, Loizos

AU - Alhabib, Khalid F.

AU - De Boer, Menko Jan

AU - Claeys, Marc J.

AU - Deleanu, Dan

AU - Dudek, Dariusz

AU - Erglis, Andrejs

AU - Gilard, Martine

AU - Goktekin, Omer

AU - Guagliumi, Giulio

AU - Gudnason, Thorarinn

AU - Hansen, Kim Wadt

AU - Huber, Kurt

AU - James, Stefan

AU - Janota, Tomáš

AU - Jennings, Siobhan

AU - Kajander, Olli

AU - Kanakakis, John

AU - Karamfiloff, Kiril K.

AU - Kedev, Sasko

AU - Kornowski, Ran

AU - Ludman, Peter F.

AU - Merkely, B.

AU - Milicic, Davor

AU - Najafov, Ruslan

AU - Nicolini, Francesca A.

AU - Noč, Marko

AU - Ostojic, Miodrag

AU - Pereira, Hélder

AU - Radovanovic, Dragana

AU - Sabaté, Manel

AU - Sobhy, Mohamed

AU - Sokolov, Maxim

AU - Studencan, Martin

AU - Terzic, Ibrahim

AU - Wahler, Steffen

AU - Widimsky, Petr

PY - 2014/8/1

Y1 - 2014/8/1

N2 - Aims: Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries. Methods and results A cross-sectional descriptive study based on aggregated country-level data on the use of reperfusion therapy in patients admitted with STEMI during 2010 or 2011. Thirty-seven ESC countries were able to provide data from existing national or regional registries. In countries where no such registries exist, data were based on best expert estimates. Data were collected on the use of STEMI reperfusion treatment and mortality, the numbers of cardiologists, and the availability of PPCI facilities in each country. Our survey provides a brief data summary of the degree of variation in reperfusion therapy across Europe. The number of PPCI procedures varied between countries, ranging from 23 to 884 per million inhabitants. Primary percutaneous coronary intervention and thrombolysis were the dominant reperfusion strategy in 33 and 4 countries, respectively. The mean population served by a single PPCI centre with a 24-h service 7 days a week ranged from 31 300 inhabitants per centre to 6 533 000 inhabitants per centre. Twenty-seven of the total 37 countries participated in a former survey from 2007, and major increases in PPCI utilization were observed in 13 of these countries. Conclusion Large variations in reperfusion treatment are still present across Europe. Countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusion therapy. Implementation of the best reperfusion therapy as recommended in the guidelines should be encouraged. All rights reserved.

AB - Aims: Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries. Methods and results A cross-sectional descriptive study based on aggregated country-level data on the use of reperfusion therapy in patients admitted with STEMI during 2010 or 2011. Thirty-seven ESC countries were able to provide data from existing national or regional registries. In countries where no such registries exist, data were based on best expert estimates. Data were collected on the use of STEMI reperfusion treatment and mortality, the numbers of cardiologists, and the availability of PPCI facilities in each country. Our survey provides a brief data summary of the degree of variation in reperfusion therapy across Europe. The number of PPCI procedures varied between countries, ranging from 23 to 884 per million inhabitants. Primary percutaneous coronary intervention and thrombolysis were the dominant reperfusion strategy in 33 and 4 countries, respectively. The mean population served by a single PPCI centre with a 24-h service 7 days a week ranged from 31 300 inhabitants per centre to 6 533 000 inhabitants per centre. Twenty-seven of the total 37 countries participated in a former survey from 2007, and major increases in PPCI utilization were observed in 13 of these countries. Conclusion Large variations in reperfusion treatment are still present across Europe. Countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusion therapy. Implementation of the best reperfusion therapy as recommended in the guidelines should be encouraged. All rights reserved.

KW - Europe

KW - Primary percutaneous coronary intervention

KW - STEMI

KW - Treatment variation

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