Repair of a vesico-vaginal fistula with amniotic membrane – Step 1 of the IDEAL recommendations of surgical innovation

Dimitri Barski, Holger Gerullis, Thorsten Ecke, Gabriella Varga, Mihaly Boros, Isabel Pintelon, Jean Pierre Timmermans, Alexander Winter, Jens Willem Bagner, Thomas Otto

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Introduction Complex vesico-vaginal fistula (VVF) has a high recurrence rate and so the repair with graft tissues seems to be favorable. Amniotic membrane (AM) plays an increasing role as a scaffold for the repair of defect tissue due to its unique biological properties with regard to promoting wound healing. Material and methods An innovative surgical procedure for AM-assisted repair of a complex vesico-vaginal fistula as the Idea Stage following the IDEAL recommendations is presented. The development of amnion preparation and the involved surgical steps are described. Results We are able to report a successful repair of VVF by abdominal approach with an amniotic membrane graft. Good functional results, no adverse events and no graft rejection have been detected. Conclusions Favorable results confirm the technical simplicity, safety and efficacy of this procedure. Following the IDEAL recommendations, consecutive animal experiments and a cohort study are in progress.

Original languageEnglish
Pages (from-to)459-461
Number of pages3
JournalCentral European Journal of Urology
Volume68
Issue number4
DOIs
Publication statusPublished - Jan 1 2015

Keywords

  • Amniotic membrane
  • IDEAL recommendations
  • Vesico-vaginal fistula

ASJC Scopus subject areas

  • Urology

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    Barski, D., Gerullis, H., Ecke, T., Varga, G., Boros, M., Pintelon, I., Timmermans, J. P., Winter, A., Bagner, J. W., & Otto, T. (2015). Repair of a vesico-vaginal fistula with amniotic membrane – Step 1 of the IDEAL recommendations of surgical innovation. Central European Journal of Urology, 68(4), 459-461. https://doi.org/10.5173/ceju.2015.683