Az adenovírusok megújult rendszertana az evolú ciós viszonyokat tükrözi. Irodalmi áttekintés

Translated title of the contribution: Renewed taxonomy of adenoviruses reflects evolutionary relations. Literature review

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

It was almost five years ago, when the author first summarized their fruitful activity in continuation of the characterization of peculiar animal adenoviruses, one of the most successful research topics initiated by late Professor ADORJÁN BARTHA. Fifteenth of December, last year was the 80th anniversary of Doctor BARTHA'S birth. The present review comprehending the newest results and their international effects is to pay homage to BARTHA'S innovative spirit. The main interest of the research team is adenovirus taxonomy. Based on the comparison of genome sequence and genome organization data and phylogenetic calculations, the classification of the family Adenoviridae has been radically changed recently. Two new genera have been established to properly classify former exceptions. The virus family Adenoviridae presently contains 4 officially accepted genera. Mastadenovirus and Aviadenovirus comprise the conventional mammalian and avian adenoviruses, respectively. One new genus was created to contain the only known frog adenovirus along with a pathogenic avian adenovirus causing different diseases in turkeys (haemorrhagic enteritis), pheasants (marble spleen disease) and chickens (splenomegaly). Common features of members in this genus are the small genome size (26 kb) and a putative sialidase gene close to the left terminus of the genome, hence the genus name is Siadenovirus. The other new genus has several members of different host origin, including the former exceptional avian adenovirus, the egg drop syndrome virus, different cattle, sheep, goat and deer viruses, and one type found in a marsupial species, the brushtail possum. The genome of these viruses is similar in size (30 kb) and in base composition (57-66% A+T). The name of this genus is Atadenovirus. Recent phylogenetic studies imply that the four present genera might correspond to four adenovirus lineages, which have co-evolved with the main vertebrate classes (mammals, birds, reptiles and amphibians). Genomic analysis of adenovirus isolates from lower vertebrates (snakes, lizards, fish) seems to support this hypothesis.

Original languageHungarian
Pages (from-to)205-211
Number of pages7
JournalMagyar Allatorvosok Lapja
Volume126
Issue number4
Publication statusPublished - Apr 1 2004

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ASJC Scopus subject areas

  • veterinary(all)

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