Renal involvement in Crohn's disease: Granulomatous inflammation in the form of mass lesion

Dávid Semjén, Zoltán Fábos, Ferenc Pakodi, A. Vincze, Imre Szabó, Péter Degrell, Mónika Csete, T. Tornóczky

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Extraintestinal manifestations of Crohn's disease (CD) are varied and concentrated mainly to the skin and eye. Urinary tract or renal involvement is extremely rare. Herein we report on a case of renal lesion of a 50-year-old woman with a 15-year history of CD. Abdominal computed tomography scan of the patient identified heterogeneous multinodular mass lesions in the left kidney. Histology proved classic granulomatous inflammatory nodules with multinucleated giant cells, eosinophils, plasma cells, epithelioid cells, and spindle-shaped myofibroblasts in the areas, where the computed tomography scan indicated. After the extensive PubMed search in the literature, this is the first macroscopically documented and histologically proved, mass-like renal involvement in CD. From now on, differential diagnostics of renal mass lesions in CD should include the tumor-like, Crohn's-type granulomatous inflammation as direct kidney manifestation of the disease.

Original languageEnglish
Pages (from-to)1267-1269
Number of pages3
JournalEuropean Journal of Gastroenterology and Hepatology
Volume23
Issue number12
DOIs
Publication statusPublished - Nov 2011

Fingerprint

Crohn Disease
Inflammation
Kidney
Tomography
Epithelioid Cells
Myofibroblasts
Kidney Diseases
Giant Cells
Plasma Cells
Urinary Tract
Eosinophils
PubMed
Histology
Skin
Neoplasms

Keywords

  • Crohn's disease
  • extraintestinal involvement
  • inflammatory bowel disease
  • inflammatory pseudotumor
  • kidney involvement

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Renal involvement in Crohn's disease : Granulomatous inflammation in the form of mass lesion. / Semjén, Dávid; Fábos, Zoltán; Pakodi, Ferenc; Vincze, A.; Szabó, Imre; Degrell, Péter; Csete, Mónika; Tornóczky, T.

In: European Journal of Gastroenterology and Hepatology, Vol. 23, No. 12, 11.2011, p. 1267-1269.

Research output: Contribution to journalArticle

Semjén, Dávid ; Fábos, Zoltán ; Pakodi, Ferenc ; Vincze, A. ; Szabó, Imre ; Degrell, Péter ; Csete, Mónika ; Tornóczky, T. / Renal involvement in Crohn's disease : Granulomatous inflammation in the form of mass lesion. In: European Journal of Gastroenterology and Hepatology. 2011 ; Vol. 23, No. 12. pp. 1267-1269.
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