Removal of selected pharmaceuticals from aqueous matrices with activated carbon under flow conditions

Mohammed ELAbadsa, Margit Varga, V. Mihucz

Research output: Contribution to journalArticle

Abstract

Removal of three selected pharmaceuticals namely, diclofenac (DCL), naproxen (NPR) and carbamazepine (CRB) was investigated in aqueous matrices using fixed-bed columns packed with granular activated carbon (GAC) under flow conditions. Model individual, three-component solutions, model sewage water (MSW) and secondary sewage water (SSW) spiked with 5 mg L−1 of pharmaceuticals were studied. Effects of GAC amount (i.e., 4, 8, 12 g), flow rate (i.e., 40, 60, 100 mL min−1), and GAC particle size (i.e., 0.42–0.82, 0.82–1.0 and 1.0–1.7 mm) on the breakthrough curve were investigated. For each column bed, an adequate flow rate could be chosen for which the outlet-to-inlet concentration ratio (C C0 −1) remained below 0.05 for 20 L outflow volume. Above 1 mm particle size, the increase in the void volume decreased the efficiency of adsorption by 30–40%. The adsorption order of compounds changed from NPR > CBR > DCL to CBR > NPR > DCL for the single and the three-component model solutions, respectively. For the SSW, the adsorption order remained the same but its efficiency decreased by 15, 17 and 25% compared to the MSW for CRB, NPR and DCL, respectively, by applying the same conditions. Nevertheless, the removal efficiency in the optimal case for SSW was ≥95% and ≥80% at the mg L−1 and μg L−1 concentration levels, respectively. The adsorption process was simulated for MSW and SSW by the Adams-Bohart and Thomas models.

Original languageEnglish
Article number104079
JournalMicrochemical Journal
Volume150
DOIs
Publication statusPublished - Nov 1 2019

Fingerprint

Sewage
Activated carbon
Naproxen
Diclofenac
Water
Pharmaceutical Preparations
Adsorption
Carbamazepine
Particle size
Flow rate

Keywords

  • Adsorption
  • Carbamazepine
  • Diclofenac
  • Fixed-bed column
  • Granular activated carbon
  • Naproxen

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

Cite this

Removal of selected pharmaceuticals from aqueous matrices with activated carbon under flow conditions. / ELAbadsa, Mohammed; Varga, Margit; Mihucz, V.

In: Microchemical Journal, Vol. 150, 104079, 01.11.2019.

Research output: Contribution to journalArticle

@article{906862e8f1154790b4092240ba23724f,
title = "Removal of selected pharmaceuticals from aqueous matrices with activated carbon under flow conditions",
abstract = "Removal of three selected pharmaceuticals namely, diclofenac (DCL), naproxen (NPR) and carbamazepine (CRB) was investigated in aqueous matrices using fixed-bed columns packed with granular activated carbon (GAC) under flow conditions. Model individual, three-component solutions, model sewage water (MSW) and secondary sewage water (SSW) spiked with 5 mg L−1 of pharmaceuticals were studied. Effects of GAC amount (i.e., 4, 8, 12 g), flow rate (i.e., 40, 60, 100 mL min−1), and GAC particle size (i.e., 0.42–0.82, 0.82–1.0 and 1.0–1.7 mm) on the breakthrough curve were investigated. For each column bed, an adequate flow rate could be chosen for which the outlet-to-inlet concentration ratio (C C0 −1) remained below 0.05 for 20 L outflow volume. Above 1 mm particle size, the increase in the void volume decreased the efficiency of adsorption by 30–40{\%}. The adsorption order of compounds changed from NPR > CBR > DCL to CBR > NPR > DCL for the single and the three-component model solutions, respectively. For the SSW, the adsorption order remained the same but its efficiency decreased by 15, 17 and 25{\%} compared to the MSW for CRB, NPR and DCL, respectively, by applying the same conditions. Nevertheless, the removal efficiency in the optimal case for SSW was ≥95{\%} and ≥80{\%} at the mg L−1 and μg L−1 concentration levels, respectively. The adsorption process was simulated for MSW and SSW by the Adams-Bohart and Thomas models.",
keywords = "Adsorption, Carbamazepine, Diclofenac, Fixed-bed column, Granular activated carbon, Naproxen",
author = "Mohammed ELAbadsa and Margit Varga and V. Mihucz",
year = "2019",
month = "11",
day = "1",
doi = "10.1016/j.microc.2019.104079",
language = "English",
volume = "150",
journal = "Microchemical Journal",
issn = "0026-265X",
publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Removal of selected pharmaceuticals from aqueous matrices with activated carbon under flow conditions

AU - ELAbadsa, Mohammed

AU - Varga, Margit

AU - Mihucz, V.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Removal of three selected pharmaceuticals namely, diclofenac (DCL), naproxen (NPR) and carbamazepine (CRB) was investigated in aqueous matrices using fixed-bed columns packed with granular activated carbon (GAC) under flow conditions. Model individual, three-component solutions, model sewage water (MSW) and secondary sewage water (SSW) spiked with 5 mg L−1 of pharmaceuticals were studied. Effects of GAC amount (i.e., 4, 8, 12 g), flow rate (i.e., 40, 60, 100 mL min−1), and GAC particle size (i.e., 0.42–0.82, 0.82–1.0 and 1.0–1.7 mm) on the breakthrough curve were investigated. For each column bed, an adequate flow rate could be chosen for which the outlet-to-inlet concentration ratio (C C0 −1) remained below 0.05 for 20 L outflow volume. Above 1 mm particle size, the increase in the void volume decreased the efficiency of adsorption by 30–40%. The adsorption order of compounds changed from NPR > CBR > DCL to CBR > NPR > DCL for the single and the three-component model solutions, respectively. For the SSW, the adsorption order remained the same but its efficiency decreased by 15, 17 and 25% compared to the MSW for CRB, NPR and DCL, respectively, by applying the same conditions. Nevertheless, the removal efficiency in the optimal case for SSW was ≥95% and ≥80% at the mg L−1 and μg L−1 concentration levels, respectively. The adsorption process was simulated for MSW and SSW by the Adams-Bohart and Thomas models.

AB - Removal of three selected pharmaceuticals namely, diclofenac (DCL), naproxen (NPR) and carbamazepine (CRB) was investigated in aqueous matrices using fixed-bed columns packed with granular activated carbon (GAC) under flow conditions. Model individual, three-component solutions, model sewage water (MSW) and secondary sewage water (SSW) spiked with 5 mg L−1 of pharmaceuticals were studied. Effects of GAC amount (i.e., 4, 8, 12 g), flow rate (i.e., 40, 60, 100 mL min−1), and GAC particle size (i.e., 0.42–0.82, 0.82–1.0 and 1.0–1.7 mm) on the breakthrough curve were investigated. For each column bed, an adequate flow rate could be chosen for which the outlet-to-inlet concentration ratio (C C0 −1) remained below 0.05 for 20 L outflow volume. Above 1 mm particle size, the increase in the void volume decreased the efficiency of adsorption by 30–40%. The adsorption order of compounds changed from NPR > CBR > DCL to CBR > NPR > DCL for the single and the three-component model solutions, respectively. For the SSW, the adsorption order remained the same but its efficiency decreased by 15, 17 and 25% compared to the MSW for CRB, NPR and DCL, respectively, by applying the same conditions. Nevertheless, the removal efficiency in the optimal case for SSW was ≥95% and ≥80% at the mg L−1 and μg L−1 concentration levels, respectively. The adsorption process was simulated for MSW and SSW by the Adams-Bohart and Thomas models.

KW - Adsorption

KW - Carbamazepine

KW - Diclofenac

KW - Fixed-bed column

KW - Granular activated carbon

KW - Naproxen

UR - http://www.scopus.com/inward/record.url?scp=85069560863&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85069560863&partnerID=8YFLogxK

U2 - 10.1016/j.microc.2019.104079

DO - 10.1016/j.microc.2019.104079

M3 - Article

AN - SCOPUS:85069560863

VL - 150

JO - Microchemical Journal

JF - Microchemical Journal

SN - 0026-265X

M1 - 104079

ER -