Focal and generalized seizures were elicited in rabbits by intracortical application of 0.3 mg ACh. The electrical activities were measured on both cortices at corresponding points and in several subcortical structures, including the reticular formation, caudate nucleus, centrum medianum, n. anterodorsalis thalami and the globus pallidus. Cross-correlation analysis and coherence spectra of longer intervals of both cortical and subcortical activities mostly showed an independence of cortical and subcortical generators. Sometimes longer values of cross-correlation were found during short periods of low voltage fast activity. Occasionally an interhemispheric projection of slow wave activity was demonstrated by coherence and cross-correlation analysis with a time delay of about 30 msec, suggesting a rare but nevertheless important interdependence between the 2 hemispheres during epileptic seizures.
|Pages (from-to)||No. E 293|
|Journal||Electroencephalography and Clinical Neurophysiology|
|Publication status||Published - Jan 1 1977|
ASJC Scopus subject areas
- Clinical Neurology