Relationship between the tissue redox state potential and dak/dt changes of [K+]0 activity during k-strophantoside or acetylcholine induced contractures.

I. Wittmann, A. Puppi, M. Dely

Research output: Contribution to journalArticle

Abstract

It was established that oxidosis evoked by methylene blue during k-strophantoside and acetylcholine contractures in skeletal muscle was accompanied by an increase in the changes of [K+]0 activity, while redosis evoked by ascorbate under the same conditions was accompanied by a decrease in the changes of [K+]0 activity. These changes in [K+]0 activity parallelled the alterations of contractures caused by oxidosis or redosis suggesting that changes in the [K+]0 transient play an important role in these phenomena.

Original languageEnglish
Pages (from-to)233-236
Number of pages4
JournalActa Physiologica Academiae Scientiarum Hungaricae
Volume60
Issue number4
Publication statusPublished - 1982

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Contracture
Acetylcholine
Oxidation-Reduction
Methylene Blue
Skeletal Muscle

ASJC Scopus subject areas

  • Physiology

Cite this

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abstract = "It was established that oxidosis evoked by methylene blue during k-strophantoside and acetylcholine contractures in skeletal muscle was accompanied by an increase in the changes of [K+]0 activity, while redosis evoked by ascorbate under the same conditions was accompanied by a decrease in the changes of [K+]0 activity. These changes in [K+]0 activity parallelled the alterations of contractures caused by oxidosis or redosis suggesting that changes in the [K+]0 transient play an important role in these phenomena.",
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AU - Puppi, A.

AU - Dely, M.

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N2 - It was established that oxidosis evoked by methylene blue during k-strophantoside and acetylcholine contractures in skeletal muscle was accompanied by an increase in the changes of [K+]0 activity, while redosis evoked by ascorbate under the same conditions was accompanied by a decrease in the changes of [K+]0 activity. These changes in [K+]0 activity parallelled the alterations of contractures caused by oxidosis or redosis suggesting that changes in the [K+]0 transient play an important role in these phenomena.

AB - It was established that oxidosis evoked by methylene blue during k-strophantoside and acetylcholine contractures in skeletal muscle was accompanied by an increase in the changes of [K+]0 activity, while redosis evoked by ascorbate under the same conditions was accompanied by a decrease in the changes of [K+]0 activity. These changes in [K+]0 activity parallelled the alterations of contractures caused by oxidosis or redosis suggesting that changes in the [K+]0 transient play an important role in these phenomena.

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