Relationship between Skin Bacterial Colonization and the Occurrence of Allergen-specific and Non-Allergen-specific Antibodies in Sera of Children with Atopic Eczema/Dermatitis Syndrome

Erzsébet Szakos, Gabriella Lakos, M. Aleksza, J. Hunyadi, Mária Farkas, Enikö Sólyom, S. Sipka

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In this study we investigated skin bacterial colonization, allergen-specific IgE and antiphospholipid/antinuclear antibodies in 72 children with atopic eczema/dermatitis syndrome (age 2-17 years). Bacteria were found on the skin in 41 cases and serological allergen-specific IgE positivity in 37. The different forms of antibodies appeared in the ratio 21/72 (33 antibodies in 21 children). The occurrence of antiphospholipid antibodies was significantly higher in the patients than in the controls. There were significantly more allergens in the group with bacterial colonization than in the group without colonization. The SCORAD index showed a significant positive association with the skin colonization. We conclude that there are significant relationships between the occurrence of Staphylococcus aureus colonization and the levels of inhalant allergen-specific IgE in children with atopic eczema/dermatitis syndrome, and between the occurrence of antiphospholipid IgM positivity and atopic eczema/dermatitis syndrome.

Original languageEnglish
Pages (from-to)32-36
Number of pages5
JournalActa Dermato-Venereologica
Volume84
Issue number1
DOIs
Publication statusPublished - 2004

Fingerprint

Atopic Dermatitis
Allergens
Skin
Antibodies
Serum
Immunoglobulin E
Antiphospholipid Antibodies
Antinuclear Antibodies
Immunoglobulin M
Staphylococcus aureus
Bacteria

Keywords

  • Antiphospholipid antibody
  • Bacterial colonization
  • Inhalant allergens
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Dermatology

Cite this

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title = "Relationship between Skin Bacterial Colonization and the Occurrence of Allergen-specific and Non-Allergen-specific Antibodies in Sera of Children with Atopic Eczema/Dermatitis Syndrome",
abstract = "In this study we investigated skin bacterial colonization, allergen-specific IgE and antiphospholipid/antinuclear antibodies in 72 children with atopic eczema/dermatitis syndrome (age 2-17 years). Bacteria were found on the skin in 41 cases and serological allergen-specific IgE positivity in 37. The different forms of antibodies appeared in the ratio 21/72 (33 antibodies in 21 children). The occurrence of antiphospholipid antibodies was significantly higher in the patients than in the controls. There were significantly more allergens in the group with bacterial colonization than in the group without colonization. The SCORAD index showed a significant positive association with the skin colonization. We conclude that there are significant relationships between the occurrence of Staphylococcus aureus colonization and the levels of inhalant allergen-specific IgE in children with atopic eczema/dermatitis syndrome, and between the occurrence of antiphospholipid IgM positivity and atopic eczema/dermatitis syndrome.",
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author = "Erzs{\'e}bet Szakos and Gabriella Lakos and M. Aleksza and J. Hunyadi and M{\'a}ria Farkas and Enik{\"o} S{\'o}lyom and S. Sipka",
year = "2004",
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T1 - Relationship between Skin Bacterial Colonization and the Occurrence of Allergen-specific and Non-Allergen-specific Antibodies in Sera of Children with Atopic Eczema/Dermatitis Syndrome

AU - Szakos, Erzsébet

AU - Lakos, Gabriella

AU - Aleksza, M.

AU - Hunyadi, J.

AU - Farkas, Mária

AU - Sólyom, Enikö

AU - Sipka, S.

PY - 2004

Y1 - 2004

N2 - In this study we investigated skin bacterial colonization, allergen-specific IgE and antiphospholipid/antinuclear antibodies in 72 children with atopic eczema/dermatitis syndrome (age 2-17 years). Bacteria were found on the skin in 41 cases and serological allergen-specific IgE positivity in 37. The different forms of antibodies appeared in the ratio 21/72 (33 antibodies in 21 children). The occurrence of antiphospholipid antibodies was significantly higher in the patients than in the controls. There were significantly more allergens in the group with bacterial colonization than in the group without colonization. The SCORAD index showed a significant positive association with the skin colonization. We conclude that there are significant relationships between the occurrence of Staphylococcus aureus colonization and the levels of inhalant allergen-specific IgE in children with atopic eczema/dermatitis syndrome, and between the occurrence of antiphospholipid IgM positivity and atopic eczema/dermatitis syndrome.

AB - In this study we investigated skin bacterial colonization, allergen-specific IgE and antiphospholipid/antinuclear antibodies in 72 children with atopic eczema/dermatitis syndrome (age 2-17 years). Bacteria were found on the skin in 41 cases and serological allergen-specific IgE positivity in 37. The different forms of antibodies appeared in the ratio 21/72 (33 antibodies in 21 children). The occurrence of antiphospholipid antibodies was significantly higher in the patients than in the controls. There were significantly more allergens in the group with bacterial colonization than in the group without colonization. The SCORAD index showed a significant positive association with the skin colonization. We conclude that there are significant relationships between the occurrence of Staphylococcus aureus colonization and the levels of inhalant allergen-specific IgE in children with atopic eczema/dermatitis syndrome, and between the occurrence of antiphospholipid IgM positivity and atopic eczema/dermatitis syndrome.

KW - Antiphospholipid antibody

KW - Bacterial colonization

KW - Inhalant allergens

KW - Staphylococcus aureus

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