Relationship between Skin Bacterial Colonization and the Occurrence of Allergen-specific and Non-Allergen-specific Antibodies in Sera of Children with Atopic Eczema/Dermatitis Syndrome

Erzsébet Szakos, Gabriella Lakos, Magdolna Aleksza, János Hunyadi, Mária Farkas, Enikö Sólyom, Sándor Sipka

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In this study we investigated skin bacterial colonization, allergen-specific IgE and antiphospholipid/antinuclear antibodies in 72 children with atopic eczema/dermatitis syndrome (age 2-17 years). Bacteria were found on the skin in 41 cases and serological allergen-specific IgE positivity in 37. The different forms of antibodies appeared in the ratio 21/72 (33 antibodies in 21 children). The occurrence of antiphospholipid antibodies was significantly higher in the patients than in the controls. There were significantly more allergens in the group with bacterial colonization than in the group without colonization. The SCORAD index showed a significant positive association with the skin colonization. We conclude that there are significant relationships between the occurrence of Staphylococcus aureus colonization and the levels of inhalant allergen-specific IgE in children with atopic eczema/dermatitis syndrome, and between the occurrence of antiphospholipid IgM positivity and atopic eczema/dermatitis syndrome.

Original languageEnglish
Pages (from-to)32-36
Number of pages5
JournalActa Dermato-Venereologica
Issue number1
Publication statusPublished - Feb 16 2004



  • Antiphospholipid antibody
  • Bacterial colonization
  • Inhalant allergens
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Dermatology

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