Related topic: Use of PAMPA and artificial membranes

Bálint Sinkó, K. Takács-Novák

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The following paragraphs describe the options of applying artificial membranes for the prediction of transdermal penetration, focusing mostly on the PAMPA method. A model membrane of PAMPA mimicking skin penetration was first described in 2006, but the need for a more bio-mimetic system has arisen with new industrial tendencies, and a more bio-relevant system was published in 2012. Since its first publication, Skin PAMPA has already been applied by several universities and industrial groups successfully and the first articles, podium, and poster presentations have appeared. Application of the Skin PAMPA model has been extended and examples for testing of semi-solid formulations and transdermal patches are available, besides the standard solution applications.

Original languageEnglish
Title of host publicationSkin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds
PublisherSpringer Japan
Pages391-397
Number of pages7
ISBN (Electronic)9784431565260
ISBN (Print)9784431565246
DOIs
Publication statusPublished - Nov 28 2017

Fingerprint

Artificial Membranes
Skin
Membranes
Transdermal Patch
Posters
Publications
Testing

Keywords

  • API screening
  • Excipient selection
  • Formulation development
  • Formulation ranking
  • Penetration enhancer testing
  • Skin penetration
  • Topical formulation

ASJC Scopus subject areas

  • Medicine(all)
  • Chemistry(all)

Cite this

Sinkó, B., & Takács-Novák, K. (2017). Related topic: Use of PAMPA and artificial membranes. In Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds (pp. 391-397). Springer Japan. https://doi.org/10.1007/978-4-431-56526-0_35

Related topic : Use of PAMPA and artificial membranes. / Sinkó, Bálint; Takács-Novák, K.

Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds. Springer Japan, 2017. p. 391-397.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sinkó, B & Takács-Novák, K 2017, Related topic: Use of PAMPA and artificial membranes. in Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds. Springer Japan, pp. 391-397. https://doi.org/10.1007/978-4-431-56526-0_35
Sinkó B, Takács-Novák K. Related topic: Use of PAMPA and artificial membranes. In Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds. Springer Japan. 2017. p. 391-397 https://doi.org/10.1007/978-4-431-56526-0_35
Sinkó, Bálint ; Takács-Novák, K. / Related topic : Use of PAMPA and artificial membranes. Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds. Springer Japan, 2017. pp. 391-397
@inbook{86899283baab413092d42a2425d068ab,
title = "Related topic: Use of PAMPA and artificial membranes",
abstract = "The following paragraphs describe the options of applying artificial membranes for the prediction of transdermal penetration, focusing mostly on the PAMPA method. A model membrane of PAMPA mimicking skin penetration was first described in 2006, but the need for a more bio-mimetic system has arisen with new industrial tendencies, and a more bio-relevant system was published in 2012. Since its first publication, Skin PAMPA has already been applied by several universities and industrial groups successfully and the first articles, podium, and poster presentations have appeared. Application of the Skin PAMPA model has been extended and examples for testing of semi-solid formulations and transdermal patches are available, besides the standard solution applications.",
keywords = "API screening, Excipient selection, Formulation development, Formulation ranking, Penetration enhancer testing, Skin penetration, Topical formulation",
author = "B{\'a}lint Sink{\'o} and K. Tak{\'a}cs-Nov{\'a}k",
year = "2017",
month = "11",
day = "28",
doi = "10.1007/978-4-431-56526-0_35",
language = "English",
isbn = "9784431565246",
pages = "391--397",
booktitle = "Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds",
publisher = "Springer Japan",

}

TY - CHAP

T1 - Related topic

T2 - Use of PAMPA and artificial membranes

AU - Sinkó, Bálint

AU - Takács-Novák, K.

PY - 2017/11/28

Y1 - 2017/11/28

N2 - The following paragraphs describe the options of applying artificial membranes for the prediction of transdermal penetration, focusing mostly on the PAMPA method. A model membrane of PAMPA mimicking skin penetration was first described in 2006, but the need for a more bio-mimetic system has arisen with new industrial tendencies, and a more bio-relevant system was published in 2012. Since its first publication, Skin PAMPA has already been applied by several universities and industrial groups successfully and the first articles, podium, and poster presentations have appeared. Application of the Skin PAMPA model has been extended and examples for testing of semi-solid formulations and transdermal patches are available, besides the standard solution applications.

AB - The following paragraphs describe the options of applying artificial membranes for the prediction of transdermal penetration, focusing mostly on the PAMPA method. A model membrane of PAMPA mimicking skin penetration was first described in 2006, but the need for a more bio-mimetic system has arisen with new industrial tendencies, and a more bio-relevant system was published in 2012. Since its first publication, Skin PAMPA has already been applied by several universities and industrial groups successfully and the first articles, podium, and poster presentations have appeared. Application of the Skin PAMPA model has been extended and examples for testing of semi-solid formulations and transdermal patches are available, besides the standard solution applications.

KW - API screening

KW - Excipient selection

KW - Formulation development

KW - Formulation ranking

KW - Penetration enhancer testing

KW - Skin penetration

KW - Topical formulation

UR - http://www.scopus.com/inward/record.url?scp=85043676678&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85043676678&partnerID=8YFLogxK

U2 - 10.1007/978-4-431-56526-0_35

DO - 10.1007/978-4-431-56526-0_35

M3 - Chapter

AN - SCOPUS:85043676678

SN - 9784431565246

SP - 391

EP - 397

BT - Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds

PB - Springer Japan

ER -