Reinnervation of a single vibrissa after nerve excision in the adult rat

Jeno Páli, László Négyessy

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

After a survival time of 180 days following the excision of a 2 mm segment of the vibrissal nerve to the γ straddler vibrissa in the adult rat, a retrograde fluorescent single-labelling experiment revealed that 46% of the injured vibrissal sensory neurones had regenerated their peripheral processes. Peripheral collateral sprouting was not involved in the reinnervation of the denervated γ vibrissa, as proved by a retrograde fluorescent double-labelling experiment. The regenerating nerve fibres did not invade the intact neighbouring vibrissae of the γ vibrissa, and the sensory nerve fibres of the intact vibrissae were not translocated to the denervated γ vibrissa. Thus, the sensory function of the denervated γ vibrissa was restored exclusively by the regeneration of the damaged vibrissal nerve.

Original languageEnglish
Pages (from-to)1743-1746
Number of pages4
JournalNeuroreport
Volume13
Issue number14
DOIs
Publication statusPublished - Oct 7 2002

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Keywords

  • Collateral sprouting
  • Convergence
  • Crush lesion
  • Nerve transection
  • Regeneration
  • Translocation
  • Trigeminal

ASJC Scopus subject areas

  • Neuroscience(all)

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