Regulatory T cells and T helper subsets in breast-fed infants with hematochezia caused by allergic colitis

Áron Cseh, Kriszta Molnár, Petra Pintér, Balazs Szalay, B. Szebeni, Andras Treszl, A. Arató, B. Vásárhelyi, G. Verès

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The objective of our study was to investigate the prevalence of CD4 T lymphocyte subsets and their commitment to TH1 or TH2 direction in 10 infants with allergic colitis (AC) and 10 healthy controls. Infants with AC presented with a higher ratio of naïve to memory cells, lower prevalence of activated CD4CD25 cells and FoxP3 regulatory cells, and a shift to TH2 direction in balance compared with controls. These alterations are normalized upon cessation of AC symptoms on elemental L-amino acid formula. These findings suggest the importance of antigen exposure in AC in infancy.

Original languageEnglish
Pages (from-to)675-677
Number of pages3
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume51
Issue number5
DOIs
Publication statusPublished - Nov 2010

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Gastrointestinal Hemorrhage
Regulatory T-Lymphocytes
Colitis
Breast
T-Lymphocyte Subsets
Antigens
Amino Acids
Direction compound

Keywords

  • allergic colitis
  • food allergy
  • hematochezia
  • infants
  • lymphocyte activation

ASJC Scopus subject areas

  • Gastroenterology
  • Pediatrics, Perinatology, and Child Health

Cite this

Regulatory T cells and T helper subsets in breast-fed infants with hematochezia caused by allergic colitis. / Cseh, Áron; Molnár, Kriszta; Pintér, Petra; Szalay, Balazs; Szebeni, B.; Treszl, Andras; Arató, A.; Vásárhelyi, B.; Verès, G.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 51, No. 5, 11.2010, p. 675-677.

Research output: Contribution to journalArticle

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AU - Arató, A.

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