Regioselective Suzuki-Miyaura cross-coupling reactions of the bis(triflate) of 4,7-dihydroxycoumarin

Zien Khaddour, Omer A. Akrawi, Ali S. Suleiman, Tamás Patonay, Alexander Villinger, Peter Langer

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Arylated coumarins were prepared by site-selective Suzuki-Miyaura cross-coupling reaction of the bis(triflate) of 4,7-dihydroxycoumarin. The reactions proceeded by initial attack to the sterically more hindered position, due to electronic reasons.

Original languageEnglish
Pages (from-to)4421-4423
Number of pages3
JournalTetrahedron Letters
Volume55
Issue number32
DOIs
Publication statusPublished - Aug 6 2014

Keywords

  • Catalysis
  • Heterocycles
  • Palladium
  • Regioselectivity
  • Suzuki-Miyaura reaction

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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