Regional and temporal changes in AIDS in Europe before HAART

A. Blaxhult, Z. Fox, R. Colebunders, P. Francioli, Z. Ben-Ishai, G. Fätkenheuer, J. M. Parkin, P. Vanhems, A. N. Phillips, O. Kirk, C. Katlama, M. Dietrich, J. Kosmidis, D. Bánhegyi, F. Mulcahy, I. Yust, S. Vella, A. Chiesi, L. Viksna, S. ChaplinskasR. Hemmer, P. Reiss, J. Bruun, B. Knysz, F. Antunes, M. Mikras, J. Gonzĺez-Lahoz, A. Blaxhult, B. Ledergerber, S. Barton

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In a prospective observational study 4485 patients from 46 clinical centres in 17 European countries were followed between April 1994 and November 1996. Information on AIDS-defining events (ADEs) were collected together with basic demographic data, treatment history and laboratory results. The centres were divided into four geographical regions (north, central, south-west and south-east) so that it was possible to identify any existing regional differences in ADEs. The regional differences that we observed included a higher risk of all forms of Mycobacterium tuberculosis infections (Tb) and wasting disease in the south-west and an increased risk of infections with the Mycobacterium avium complex (MAC) in the north. In Cox multivariable analyses, where north was used as the reference group, we observed hazard ratios of 6.87, 7.77, 2.29 and 0.16 (P

Original languageEnglish
Pages (from-to)565-576
Number of pages12
JournalEpidemiology and Infection
Volume129
Issue number3
Publication statusPublished - Dec 2002

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Highly Active Antiretroviral Therapy
Acquired Immunodeficiency Syndrome
Wasting Syndrome
Mycobacterium avium Complex
Mycobacterium Infections
Mycobacterium tuberculosis
Observational Studies
History
Demography
Prospective Studies
Infection
Therapeutics

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Immunology

Cite this

Blaxhult, A., Fox, Z., Colebunders, R., Francioli, P., Ben-Ishai, Z., Fätkenheuer, G., ... Barton, S. (2002). Regional and temporal changes in AIDS in Europe before HAART. Epidemiology and Infection, 129(3), 565-576.

Regional and temporal changes in AIDS in Europe before HAART. / Blaxhult, A.; Fox, Z.; Colebunders, R.; Francioli, P.; Ben-Ishai, Z.; Fätkenheuer, G.; Parkin, J. M.; Vanhems, P.; Phillips, A. N.; Kirk, O.; Katlama, C.; Dietrich, M.; Kosmidis, J.; Bánhegyi, D.; Mulcahy, F.; Yust, I.; Vella, S.; Chiesi, A.; Viksna, L.; Chaplinskas, S.; Hemmer, R.; Reiss, P.; Bruun, J.; Knysz, B.; Antunes, F.; Mikras, M.; Gonzĺez-Lahoz, J.; Blaxhult, A.; Ledergerber, B.; Barton, S.

In: Epidemiology and Infection, Vol. 129, No. 3, 12.2002, p. 565-576.

Research output: Contribution to journalArticle

Blaxhult, A, Fox, Z, Colebunders, R, Francioli, P, Ben-Ishai, Z, Fätkenheuer, G, Parkin, JM, Vanhems, P, Phillips, AN, Kirk, O, Katlama, C, Dietrich, M, Kosmidis, J, Bánhegyi, D, Mulcahy, F, Yust, I, Vella, S, Chiesi, A, Viksna, L, Chaplinskas, S, Hemmer, R, Reiss, P, Bruun, J, Knysz, B, Antunes, F, Mikras, M, Gonzĺez-Lahoz, J, Blaxhult, A, Ledergerber, B & Barton, S 2002, 'Regional and temporal changes in AIDS in Europe before HAART', Epidemiology and Infection, vol. 129, no. 3, pp. 565-576.
Blaxhult A, Fox Z, Colebunders R, Francioli P, Ben-Ishai Z, Fätkenheuer G et al. Regional and temporal changes in AIDS in Europe before HAART. Epidemiology and Infection. 2002 Dec;129(3):565-576.
Blaxhult, A. ; Fox, Z. ; Colebunders, R. ; Francioli, P. ; Ben-Ishai, Z. ; Fätkenheuer, G. ; Parkin, J. M. ; Vanhems, P. ; Phillips, A. N. ; Kirk, O. ; Katlama, C. ; Dietrich, M. ; Kosmidis, J. ; Bánhegyi, D. ; Mulcahy, F. ; Yust, I. ; Vella, S. ; Chiesi, A. ; Viksna, L. ; Chaplinskas, S. ; Hemmer, R. ; Reiss, P. ; Bruun, J. ; Knysz, B. ; Antunes, F. ; Mikras, M. ; Gonzĺez-Lahoz, J. ; Blaxhult, A. ; Ledergerber, B. ; Barton, S. / Regional and temporal changes in AIDS in Europe before HAART. In: Epidemiology and Infection. 2002 ; Vol. 129, No. 3. pp. 565-576.
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AU - Parkin, J. M.

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AU - Chaplinskas, S.

AU - Hemmer, R.

AU - Reiss, P.

AU - Bruun, J.

AU - Knysz, B.

AU - Antunes, F.

AU - Mikras, M.

AU - Gonzĺez-Lahoz, J.

AU - Blaxhult, A.

AU - Ledergerber, B.

AU - Barton, S.

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