Regioexhaustive Functionalization of the Carbocyclic Core of Isoquinoline: Concise Synthesis of Oxoaporphine Core and Ellipticine

Dániel Vajk Horváth, Frigyes Domonyi, Roberta Palkó, Andrea Lomoschitz, Tibor Soós

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A general and versatile strategy has been developed for the functionalization of the carbocyclic core of the isoquinoline. This regioexhaustive approach employs electrophilic halogenation as a toolbox methodology and delivers highly decorated intermediates that can be further elaborated toward medicinally relevant building blocks or natural products.

Original languageEnglish
Pages (from-to)2181-2190
Number of pages10
JournalSynthesis (Germany)
Volume50
Issue number11
DOIs
Publication statusPublished - Jun 1 2018

Keywords

  • cross-coupling
  • ellipticine
  • fused-ring systems
  • hetero-cycles
  • isoquinoline
  • regioexhaustive

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Regioexhaustive Functionalization of the Carbocyclic Core of Isoquinoline: Concise Synthesis of Oxoaporphine Core and Ellipticine'. Together they form a unique fingerprint.

  • Cite this