Regeneration of toxigenic Pasteurella multocida induced severe turbinate atrophy in pigs detected by computed tomography

Tibor Magyar, Tamás Donkó, I. Repa, Melinda Kovács

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Atrophic rhinitis is a widely prevalent infectious disease of swine caused by Bordetella bronchiseptica and Pasteurella multocida. The course of the disease is considered to be different depending on the principal aetiological agents distinguishing B. bronchiseptica induced non-progressive and toxigenic P. multocida produced progressive forms. In order to compare the pathological events of the two forms of the disease, the development of nasal lesions has longitudinally been studied in pigs infected by either B. bronchiseptica alone or B. bronchiseptica and toxigenic P. multocida together using computed tomography to visualise the nasal structures.Results: B. bronchiseptica infection alone caused moderately severe nasal turbinate atrophy and these lesions completely regenerated by the time of slaughter. Unexpectedly, complete regeneration of the bony structures of the nasal cavity was also observed in pigs infected by B. bronchiseptica and toxigenic P. multocida together in spite of seeing severe turbinate atrophy in most of the infected animals around the age of six weeks.Conclusions: B. bronchiseptica mono-infection has been confirmed to cause only mild to moderate and transient lesions, at least in high health status pigs. Even severe turbinate atrophy induced by B. bronchiseptica and toxigenic P. multocida combined infection is able to be reorganised to their normal anatomical structure. Computed tomography has further been verified to be a useful tool to examine the pathological events of atrophic rhinitis in a longitudinal manner.

Original languageEnglish
Article number222
JournalBMC Veterinary Research
Volume9
DOIs
Publication statusPublished - Oct 30 2013

Fingerprint

Bordetella bronchiseptica
Pasteurella multocida
Turbinates
atrophy
computed tomography
Atrophy
Regeneration
Swine
Tomography
swine
Atrophic Rhinitis
lesions (animal)
rhinitis
Nose
Bordetella Infections
Nose Diseases
infection
nasal cavity
Nasal Cavity
etiological agents

Keywords

  • Atrophic rhinitis
  • Bordetella bronchiseptica
  • Computed tomography
  • Pasteurella multocida

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Regeneration of toxigenic Pasteurella multocida induced severe turbinate atrophy in pigs detected by computed tomography. / Magyar, Tibor; Donkó, Tamás; Repa, I.; Kovács, Melinda.

In: BMC Veterinary Research, Vol. 9, 222, 30.10.2013.

Research output: Contribution to journalArticle

@article{3678c1061b364e919fa56e38fa3f733f,
title = "Regeneration of toxigenic Pasteurella multocida induced severe turbinate atrophy in pigs detected by computed tomography",
abstract = "Background: Atrophic rhinitis is a widely prevalent infectious disease of swine caused by Bordetella bronchiseptica and Pasteurella multocida. The course of the disease is considered to be different depending on the principal aetiological agents distinguishing B. bronchiseptica induced non-progressive and toxigenic P. multocida produced progressive forms. In order to compare the pathological events of the two forms of the disease, the development of nasal lesions has longitudinally been studied in pigs infected by either B. bronchiseptica alone or B. bronchiseptica and toxigenic P. multocida together using computed tomography to visualise the nasal structures.Results: B. bronchiseptica infection alone caused moderately severe nasal turbinate atrophy and these lesions completely regenerated by the time of slaughter. Unexpectedly, complete regeneration of the bony structures of the nasal cavity was also observed in pigs infected by B. bronchiseptica and toxigenic P. multocida together in spite of seeing severe turbinate atrophy in most of the infected animals around the age of six weeks.Conclusions: B. bronchiseptica mono-infection has been confirmed to cause only mild to moderate and transient lesions, at least in high health status pigs. Even severe turbinate atrophy induced by B. bronchiseptica and toxigenic P. multocida combined infection is able to be reorganised to their normal anatomical structure. Computed tomography has further been verified to be a useful tool to examine the pathological events of atrophic rhinitis in a longitudinal manner.",
keywords = "Atrophic rhinitis, Bordetella bronchiseptica, Computed tomography, Pasteurella multocida",
author = "Tibor Magyar and Tam{\'a}s Donk{\'o} and I. Repa and Melinda Kov{\'a}cs",
year = "2013",
month = "10",
day = "30",
doi = "10.1186/1746-6148-9-222",
language = "English",
volume = "9",
journal = "BMC Veterinary Research",
issn = "1746-6148",
publisher = "BioMed Central",

}

TY - JOUR

T1 - Regeneration of toxigenic Pasteurella multocida induced severe turbinate atrophy in pigs detected by computed tomography

AU - Magyar, Tibor

AU - Donkó, Tamás

AU - Repa, I.

AU - Kovács, Melinda

PY - 2013/10/30

Y1 - 2013/10/30

N2 - Background: Atrophic rhinitis is a widely prevalent infectious disease of swine caused by Bordetella bronchiseptica and Pasteurella multocida. The course of the disease is considered to be different depending on the principal aetiological agents distinguishing B. bronchiseptica induced non-progressive and toxigenic P. multocida produced progressive forms. In order to compare the pathological events of the two forms of the disease, the development of nasal lesions has longitudinally been studied in pigs infected by either B. bronchiseptica alone or B. bronchiseptica and toxigenic P. multocida together using computed tomography to visualise the nasal structures.Results: B. bronchiseptica infection alone caused moderately severe nasal turbinate atrophy and these lesions completely regenerated by the time of slaughter. Unexpectedly, complete regeneration of the bony structures of the nasal cavity was also observed in pigs infected by B. bronchiseptica and toxigenic P. multocida together in spite of seeing severe turbinate atrophy in most of the infected animals around the age of six weeks.Conclusions: B. bronchiseptica mono-infection has been confirmed to cause only mild to moderate and transient lesions, at least in high health status pigs. Even severe turbinate atrophy induced by B. bronchiseptica and toxigenic P. multocida combined infection is able to be reorganised to their normal anatomical structure. Computed tomography has further been verified to be a useful tool to examine the pathological events of atrophic rhinitis in a longitudinal manner.

AB - Background: Atrophic rhinitis is a widely prevalent infectious disease of swine caused by Bordetella bronchiseptica and Pasteurella multocida. The course of the disease is considered to be different depending on the principal aetiological agents distinguishing B. bronchiseptica induced non-progressive and toxigenic P. multocida produced progressive forms. In order to compare the pathological events of the two forms of the disease, the development of nasal lesions has longitudinally been studied in pigs infected by either B. bronchiseptica alone or B. bronchiseptica and toxigenic P. multocida together using computed tomography to visualise the nasal structures.Results: B. bronchiseptica infection alone caused moderately severe nasal turbinate atrophy and these lesions completely regenerated by the time of slaughter. Unexpectedly, complete regeneration of the bony structures of the nasal cavity was also observed in pigs infected by B. bronchiseptica and toxigenic P. multocida together in spite of seeing severe turbinate atrophy in most of the infected animals around the age of six weeks.Conclusions: B. bronchiseptica mono-infection has been confirmed to cause only mild to moderate and transient lesions, at least in high health status pigs. Even severe turbinate atrophy induced by B. bronchiseptica and toxigenic P. multocida combined infection is able to be reorganised to their normal anatomical structure. Computed tomography has further been verified to be a useful tool to examine the pathological events of atrophic rhinitis in a longitudinal manner.

KW - Atrophic rhinitis

KW - Bordetella bronchiseptica

KW - Computed tomography

KW - Pasteurella multocida

UR - http://www.scopus.com/inward/record.url?scp=84886530081&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84886530081&partnerID=8YFLogxK

U2 - 10.1186/1746-6148-9-222

DO - 10.1186/1746-6148-9-222

M3 - Article

C2 - 24171824

AN - SCOPUS:84886530081

VL - 9

JO - BMC Veterinary Research

JF - BMC Veterinary Research

SN - 1746-6148

M1 - 222

ER -