Reexamination of cross sections of the 100Mo(p,2n)99mTc reaction

S. Takács, A. Hermanne, F. Ditrói, F. Tárkányi, M. Aikawa

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10 Citations (Scopus)

Abstract

The nuclear medicine community has been expressing concerns world wide regarding shortages of 99mTc supply based on fission production of 99Mo from highly enriched uranium (HEU) to prepare 99Mo/99mTc generators. As an alternative to reactor produced 99Mo/99mTc generator technology, the direct production of 99mTc on accelerators is considered. There are a number of methods of using accelerators to produce 99mTc and/or 99Mo. Direct production of 99mTc on highly enriched 100Mo target using cyclotrons is interesting for energies up to 20 MeV, so as to minimize the impurities from additional open reaction channels. To estimate the quality of the accelerator produced 99mTc all the possible reaction routes should be mapped which could be potentially involved in this technology. However, a well defined excitation function for the 100Mo(p,2n)99mTc primary reaction is needed, in order to achieve acceptable good results in assessing the quality of the accelerator-produced 99mTc by theoretical calculations. Most of the available experimental cross section data series for the 100Mo(p,2n)99mTc reaction have the same general shape while their amplitudes are different. A large difference more than a factor of two may, indeed, be observed between the lowest and the highest datasets values. The aim of this study was therefore to get a new evaluation for the 100Mo(p,2n)99mTc cross section, through three independent experiments, aiming at a more confident estimation about the amplitude of the excitation function.

Original languageEnglish
Pages (from-to)26-38
Number of pages13
JournalNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume347
DOIs
Publication statusPublished - Mar 15 2015

Fingerprint

Particle accelerators
accelerators
cross sections
generators
Nuclear medicine
nuclear medicine
Cyclotrons
Uranium
uranium
excitation
cyclotrons
fission
reactors
routes
Impurities
impurities
evaluation
estimates
Experiments
energy

Keywords

  • Mo
  • Tc
  • Cross section
  • Cyclotron

ASJC Scopus subject areas

  • Instrumentation
  • Nuclear and High Energy Physics

Cite this

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title = "Reexamination of cross sections of the 100Mo(p,2n)99mTc reaction",
abstract = "The nuclear medicine community has been expressing concerns world wide regarding shortages of 99mTc supply based on fission production of 99Mo from highly enriched uranium (HEU) to prepare 99Mo/99mTc generators. As an alternative to reactor produced 99Mo/99mTc generator technology, the direct production of 99mTc on accelerators is considered. There are a number of methods of using accelerators to produce 99mTc and/or 99Mo. Direct production of 99mTc on highly enriched 100Mo target using cyclotrons is interesting for energies up to 20 MeV, so as to minimize the impurities from additional open reaction channels. To estimate the quality of the accelerator produced 99mTc all the possible reaction routes should be mapped which could be potentially involved in this technology. However, a well defined excitation function for the 100Mo(p,2n)99mTc primary reaction is needed, in order to achieve acceptable good results in assessing the quality of the accelerator-produced 99mTc by theoretical calculations. Most of the available experimental cross section data series for the 100Mo(p,2n)99mTc reaction have the same general shape while their amplitudes are different. A large difference more than a factor of two may, indeed, be observed between the lowest and the highest datasets values. The aim of this study was therefore to get a new evaluation for the 100Mo(p,2n)99mTc cross section, through three independent experiments, aiming at a more confident estimation about the amplitude of the excitation function.",
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AU - Hermanne, A.

AU - Ditrói, F.

AU - Tárkányi, F.

AU - Aikawa, M.

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