Reduction and N-alkylation of α-methylene-indolines with sodium cyanoborohydride in carboxylic acids

E. R. Balogh, B. Zsadon, A. Csámpai, R. Pal

Research output: Contribution to journalArticle

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Abstract

The reaction of α-methylene-indolines with NaCNBH3 in carboxylic acids at room temperature can yield either 2β,3β-dihydro-indolines or their N- alkyl derivatives as main products with high selectively, depending mainly on the carboxylic acid and on the reaction time when using a large excess of NaCNBH3.

Original languageEnglish
Pages (from-to)701-707
Number of pages7
JournalSynthetic Communications
Volume24
Issue number5
Publication statusPublished - 1994

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Alkylation
Carboxylic Acids
Derivatives
Temperature
sodium cyanoborohydride
indoline

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Reduction and N-alkylation of α-methylene-indolines with sodium cyanoborohydride in carboxylic acids. / Balogh, E. R.; Zsadon, B.; Csámpai, A.; Pal, R.

In: Synthetic Communications, Vol. 24, No. 5, 1994, p. 701-707.

Research output: Contribution to journalArticle

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