Reduction and n-alkylation of α-methylene-indolines with sodium cyanoborohydride in carboxylic acids

Emilia R. Balogh, Béla Zsadon, Antal Csámpai, Róbert Pál, Emilia R. Balogh, Béla Zsadon, Antal Csámpai, Róbert Pál

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1 Citation (Scopus)

Abstract

The reaction of α-methylene-indolines with NaCNBH3 in carboxylic acids at room temperature can yield either 2ß,3(ß-dihydro-indolines or their N-alkyl derivatives as main products with high selectivity, depending mainly on the carboxylic acid and on the reaction time when using a large excess of NaCNBH3.

Original languageEnglish
Pages (from-to)701-707
Number of pages7
JournalSynthetic Communications
Volume24
Issue number5
DOIs
Publication statusPublished - Mar 1 1994

ASJC Scopus subject areas

  • Organic Chemistry

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