Redox status of dogs with non-hodgkin lymphomas. An ESR study

Péter Vajdovich, Tamás Kriska, Miklós Mézes, Piroska Ribiczey Szabó, Nándor Balogh, András Bánfi, Attila Arany-Tóth, Tibor Gaál, Judit Jakus

Research output: Contribution to journalArticle

14 Citations (Scopus)


Free radical and antioxidant parameters in healthy dogs (n=10) and dogs with non-Hodgkin lymphomas (n=11) were measured in blood and lymph node tissue samples before chemotherapy. Enzymatic and other biochemical measurements were performed. We found that (i) free radical concentrations based on ESR spectra of tissues correlated with higher proliferative character; (ii) lymphoma cases showed an impaired antioxidant status; (iii) tumors with low oxidative burst capacity and higher reduced/oxidized glutathione ratio responded better to chemotherapy; and (iv) affected blood and lymph nodes were under strong oxidative stress.

Original languageEnglish
Pages (from-to)339-346
Number of pages8
JournalCancer Letters
Issue number2
Publication statusPublished - Jun 28 2005


  • Antioxidant
  • Canine lymphoma
  • Free radicals
  • MDR
  • Oxidative burst
  • Prognosis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Redox status of dogs with non-hodgkin lymphomas. An ESR study'. Together they form a unique fingerprint.

  • Cite this

    Vajdovich, P., Kriska, T., Mézes, M., Szabó, P. R., Balogh, N., Bánfi, A., Arany-Tóth, A., Gaál, T., & Jakus, J. (2005). Redox status of dogs with non-hodgkin lymphomas. An ESR study. Cancer Letters, 224(2), 339-346.