Red Cell Distribution Width and Mortality in Hemodialysis Patients

Tania Vashistha, Elani Streja, M. Molnár, Connie M. Rhee, Hamid Moradi, Melissa Soohoo, Csaba P. Kovesdy, Kamyar Kalantar-Zadeh

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background: Red cell distribution width (RDW) is an index of red blood cell volume variability that has historically been used as a marker of iron deficiency anemia. More recently, studies have shown that elevated RDW is associated with higher mortality risk in the general population. However, there is lack of data demonstrating the association between RDW and mortality risk in hemodialysis (HD) patients. We hypothesized that higher RDW is associated with higher mortality in HD patients. Study Design: Retrospective observational study using a large HD patient cohort. Setting & Participants: 109,675 adult maintenance HD patients treated in a large dialysis organization from January 1, 2007, to December 31, 2011. Predictor: Baseline and time-varying RDW, grouped into 5 categories:

Original languageEnglish
JournalAmerican Journal of Kidney Diseases
DOIs
Publication statusAccepted/In press - Jun 27 2015

Fingerprint

Erythrocyte Indices
Renal Dialysis
Mortality
Iron-Deficiency Anemias
Blood Volume
Cell Size
Observational Studies
Dialysis
Retrospective Studies
Erythrocytes
Maintenance
Organizations
Population

Keywords

  • End-stage renal disease (ESRD)
  • Hemodialysis (HD)
  • Mortality
  • Red blood cell heterogeneity
  • Red cell distribution width (RDW)
  • Renal function

ASJC Scopus subject areas

  • Nephrology

Cite this

Vashistha, T., Streja, E., Molnár, M., Rhee, C. M., Moradi, H., Soohoo, M., ... Kalantar-Zadeh, K. (Accepted/In press). Red Cell Distribution Width and Mortality in Hemodialysis Patients. American Journal of Kidney Diseases. https://doi.org/10.1053/j.ajkd.2015.11.020

Red Cell Distribution Width and Mortality in Hemodialysis Patients. / Vashistha, Tania; Streja, Elani; Molnár, M.; Rhee, Connie M.; Moradi, Hamid; Soohoo, Melissa; Kovesdy, Csaba P.; Kalantar-Zadeh, Kamyar.

In: American Journal of Kidney Diseases, 27.06.2015.

Research output: Contribution to journalArticle

Vashistha, Tania ; Streja, Elani ; Molnár, M. ; Rhee, Connie M. ; Moradi, Hamid ; Soohoo, Melissa ; Kovesdy, Csaba P. ; Kalantar-Zadeh, Kamyar. / Red Cell Distribution Width and Mortality in Hemodialysis Patients. In: American Journal of Kidney Diseases. 2015.
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