Recurrent phyllodes tumor in a man

Zsuzsanna Kahán, Anna M. Tószegi, Ferenc Szarvas, György Gaizer, Gyula Baradnay, Jenõ Ormos

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6 Citations (Scopus)

Abstract

The case of a 35-year-old man with a borderline-type cystosarcoma phyllodes is presented. Four years after the primary excision of the tumor, wide excision of a local recurrence and postoperative radiotherapy were performed. No repeated relapse was observed during a 5-year follow-up. Neither significant endocrine changes nor genetic alteration could be proven. However, a slightly increased SHBG concentration was detected, resulting in a decreased biologically available androgen level reduced testosterone/SHBG index. This phenomenon might be a consequence of the chronic liver disease of the patient due to his type II diabetes mellitus and alcohol abuse. In addition to the conventional histopathological examinations, immunohistochemical and electronmicroscope investigations were carried out on tissue sections, and the steroid receptors, EGF receptors and EGF-like activity of the tumor were also studied.

Original languageEnglish
Pages (from-to)653-658
Number of pages6
JournalPathology Research and Practice
Volume193
Issue number9
DOIs
Publication statusPublished - Jan 1 1997

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Keywords

  • Breast neoplasmas
  • Cystosarcoma phyllodes
  • Local therapy
  • Prognostic factors
  • Sex hormones

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cell Biology

Cite this

Kahán, Z., Tószegi, A. M., Szarvas, F., Gaizer, G., Baradnay, G., & Ormos, J. (1997). Recurrent phyllodes tumor in a man. Pathology Research and Practice, 193(9), 653-658. https://doi.org/10.1016/S0344-0338(97)80047-7