Recoverable fluorous CBS methodology for asymmetric reduction of ketones

Zoltán Dalicsek, Ferenc Pollreisz, Ágnes Gömöry, Tibor Soós

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

(Chemical Equation Presented) An operationally simple and recoverable fluorous CBS methodology was developed. The in situ-generated fluorous oxazaborolidine efficiently catalyzed the reduction of ketones with high enantioselectivity and reactivity. The subsequent recycling of the fluorous prolinol precatalyst was achieved by fluorous solid-phase extraction.

Original languageEnglish
Pages (from-to)3243-3246
Number of pages4
JournalOrganic Letters
Volume7
Issue number15
DOIs
Publication statusPublished - Jul 21 2005

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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