Recommendations from GEC ESTRO Breast Cancer Working Group (I): Target definition and target delineation for accelerated or boost Partial Breast Irradiation using multicatheter interstitial brachytherapy after breast conserving closed cavity surgery

Working Group Breast Cancer of GEC-ESTRO

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

OBJECTIVE: The aim was to develop a delineation guideline for target definition for APBI or boost by consensus of the Breast Working Group of GEC-ESTRO.

PROPOSED RECOMMENDATIONS: Appropriate delineation of CTV (PTV) with low inter- and intra-observer variability in clinical practice is complex and needs various steps as: (1) Detailed knowledge of primary surgical procedure, of all details of pathology, as well as of preoperative imaging. (2) Definition of tumour localization before breast conserving surgery inside the breast and translation of this information in the postoperative CT imaging data set. (3) Calculation of the size of total safety margins. The size should be at least 2 cm. (4) Definition of the target. (5) Delineation of the target according to defined rules.

CONCLUSION: Providing guidelines based on the consensus of a group of experts should make it possible to achieve a reproducible and consistent definition of CTV (PTV) for Accelerated Partial Breast Irradiation (APBI) or boost irradiation after breast conserving closed cavity surgery, and helps to define it after selected cases of oncoplastic surgery.

Original languageEnglish
Pages (from-to)342-348
Number of pages7
JournalRadiotherapy and Oncology
Volume115
Issue number3
DOIs
Publication statusPublished - Jun 1 2015

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Brachytherapy
Breast
Breast Neoplasms
Guidelines
Observer Variation
Segmental Mastectomy
Pathology
Safety
Neoplasms

Keywords

  • APBI
  • Boost
  • Brachytherapy
  • Breast cancer
  • Target definition

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Recommendations from GEC ESTRO Breast Cancer Working Group (I): Target definition and target delineation for accelerated or boost Partial Breast Irradiation using multicatheter interstitial brachytherapy after breast conserving closed cavity surgery",
abstract = "OBJECTIVE: The aim was to develop a delineation guideline for target definition for APBI or boost by consensus of the Breast Working Group of GEC-ESTRO.PROPOSED RECOMMENDATIONS: Appropriate delineation of CTV (PTV) with low inter- and intra-observer variability in clinical practice is complex and needs various steps as: (1) Detailed knowledge of primary surgical procedure, of all details of pathology, as well as of preoperative imaging. (2) Definition of tumour localization before breast conserving surgery inside the breast and translation of this information in the postoperative CT imaging data set. (3) Calculation of the size of total safety margins. The size should be at least 2 cm. (4) Definition of the target. (5) Delineation of the target according to defined rules.CONCLUSION: Providing guidelines based on the consensus of a group of experts should make it possible to achieve a reproducible and consistent definition of CTV (PTV) for Accelerated Partial Breast Irradiation (APBI) or boost irradiation after breast conserving closed cavity surgery, and helps to define it after selected cases of oncoplastic surgery.",
keywords = "APBI, Boost, Brachytherapy, Breast cancer, Target definition",
author = "{Working Group Breast Cancer of GEC-ESTRO} and Vratislav Strnad and Hannoun-Levi, {Jean Michel} and Guinot, {Jose Luis} and Kristina L{\"o}ssl and Daniela Kauer-Dorner and Alexandra Resch and Gy{\"o}rgy Kov{\'a}cs and T. Major and {Van Limbergen}, Erik",
year = "2015",
month = "6",
day = "1",
doi = "10.1016/j.radonc.2015.06.010",
language = "English",
volume = "115",
pages = "342--348",
journal = "Radiotherapy and Oncology",
issn = "0167-8140",
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TY - JOUR

T1 - Recommendations from GEC ESTRO Breast Cancer Working Group (I)

T2 - Target definition and target delineation for accelerated or boost Partial Breast Irradiation using multicatheter interstitial brachytherapy after breast conserving closed cavity surgery

AU - Working Group Breast Cancer of GEC-ESTRO

AU - Strnad, Vratislav

AU - Hannoun-Levi, Jean Michel

AU - Guinot, Jose Luis

AU - Lössl, Kristina

AU - Kauer-Dorner, Daniela

AU - Resch, Alexandra

AU - Kovács, György

AU - Major, T.

AU - Van Limbergen, Erik

PY - 2015/6/1

Y1 - 2015/6/1

N2 - OBJECTIVE: The aim was to develop a delineation guideline for target definition for APBI or boost by consensus of the Breast Working Group of GEC-ESTRO.PROPOSED RECOMMENDATIONS: Appropriate delineation of CTV (PTV) with low inter- and intra-observer variability in clinical practice is complex and needs various steps as: (1) Detailed knowledge of primary surgical procedure, of all details of pathology, as well as of preoperative imaging. (2) Definition of tumour localization before breast conserving surgery inside the breast and translation of this information in the postoperative CT imaging data set. (3) Calculation of the size of total safety margins. The size should be at least 2 cm. (4) Definition of the target. (5) Delineation of the target according to defined rules.CONCLUSION: Providing guidelines based on the consensus of a group of experts should make it possible to achieve a reproducible and consistent definition of CTV (PTV) for Accelerated Partial Breast Irradiation (APBI) or boost irradiation after breast conserving closed cavity surgery, and helps to define it after selected cases of oncoplastic surgery.

AB - OBJECTIVE: The aim was to develop a delineation guideline for target definition for APBI or boost by consensus of the Breast Working Group of GEC-ESTRO.PROPOSED RECOMMENDATIONS: Appropriate delineation of CTV (PTV) with low inter- and intra-observer variability in clinical practice is complex and needs various steps as: (1) Detailed knowledge of primary surgical procedure, of all details of pathology, as well as of preoperative imaging. (2) Definition of tumour localization before breast conserving surgery inside the breast and translation of this information in the postoperative CT imaging data set. (3) Calculation of the size of total safety margins. The size should be at least 2 cm. (4) Definition of the target. (5) Delineation of the target according to defined rules.CONCLUSION: Providing guidelines based on the consensus of a group of experts should make it possible to achieve a reproducible and consistent definition of CTV (PTV) for Accelerated Partial Breast Irradiation (APBI) or boost irradiation after breast conserving closed cavity surgery, and helps to define it after selected cases of oncoplastic surgery.

KW - APBI

KW - Boost

KW - Brachytherapy

KW - Breast cancer

KW - Target definition

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