Recombinant Mycobacterium smegmatis vaccine candidates

Ildikó Faludi, Ágnes Míra Szabó, Katalin Burián, Valéria Endrész, A. Miczák

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Mycobacterium smegmatis is a species of rapidly growing saprophytes with a number of properties that make it an effective vaccine vector. Recombinant M. smegmatis expressing protective antigens of different pathogens and molecules modulating the immune responses offers some potential for reduction of the burden of tuberculosis, HIV and hepatitis B infections. This paper discusses the molecular methods used to generate recombinant M. smegmatis and the results obtained with some of these recombinants.

Original languageEnglish
Pages (from-to)13-22
Number of pages10
JournalActa microbiologica et immunologica Hungarica
Volume58
Issue number1
DOIs
Publication statusPublished - Mar 1 2011

Keywords

  • Mycobacterium smegmatis
  • recombinant technology
  • vaccination

ASJC Scopus subject areas

  • Immunology and Microbiology(all)

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