Receptor-level interrelationships of amino acids and the adequate amino acid type hormones in Tetrahymena: A receptor evolution model

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Histidine stimulates the phagocytosis of Tetrahymena to the same extent as histamine, and also stimulates its division, which histamine does not. Tyrosine and diiodotyrosine equally stimulate the growth of the Tetrahymena. Both amino acids inhibit the characteristic influence of the adequate amino acid hormone when added to Tetrahymena culture 72 h in advance of it. Primary interaction with diiodotyrosine and tyrosine notably increases the cellular growth rate. Histamine has a similar, although less notable effect than histidine. In the light of these experimental observations there is reason to postulate that the receptors of the amino acid hormones have developed from amino acid receptors.

Original languageEnglish
Pages (from-to)55-59
Number of pages5
Issue number1
Publication statusPublished - 1986



  • Amino acids
  • Hormones
  • Receptor evolution
  • Tetrahymena
  • Unicellular model

ASJC Scopus subject areas

  • Statistics and Probability
  • Modelling and Simulation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Applied Mathematics

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