Újabb eredmények a BHV-4 kutatásában

Translated title of the contribution: Recent developments in research involving BHV-4

Research output: Contribution to journalArticle

Abstract

Bovine herpesvirus type 4 is widespread in cattle populations all over the world. Even though the virus is not a direct pathogen, it is an important agent because of research purposes and its role in secondary infections. The paper summarises the results of foreign and domestic laboratories from the last five years. Most important results of foreign research groups were the identification of a protein which play a role in virus-cell interaction, some data about the replication cycle, and a detailed study of viral DNA, which provided new evidence for classification of this virus into the Gammaherpesvirinae subfamily. Since the first BHV-4 strain was Isolated In Hungary (BARTHA, 1963), this virus has always been one of the prime targets of their research activities. In animal experiments they studied the spread, distribution, viraemia, latency of the virus by several methods, such as polymerase chain reaction, immuno-histochemistry and virus isolation. The virus possesses some features of Beta- and Gammaherpesviruses. During infection the virus is bound mostly to the respiratory and immune system, persists very long in leukocytes, it appears periodically in blood serum and establishes persistent infection in neural and immune tissues. By decreasing in vitro mitotic activity of leukocytes the virus might play a role in inhibiting some immune functions.

Original languageHungarian
Pages (from-to)196-199
Number of pages4
JournalMagyar Allatorvosok Lapja
Volume121
Issue number4
Publication statusPublished - 1999

Fingerprint

Viruses
viruses
Research
Gammaherpesvirinae
Bovine Herpesvirus 4
Leukocytes
Virus Latency
leukocytes
Social Identification
Bovine herpesvirus 4
Hungary
Viremia
Viral DNA
Virus Diseases
Coinfection
Cell Communication
Respiratory System
animal experimentation
viremia
Immune System

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Újabb eredmények a BHV-4 kutatásában. / Egyed, L.

In: Magyar Allatorvosok Lapja, Vol. 121, No. 4, 1999, p. 196-199.

Research output: Contribution to journalArticle

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