Recent development in the chemistry of 4,5-dihalo-3(2H)-pyridazinones

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4,5-Dihalo-3(2H)-pyridazinones have gained increasing importance in the synthetic chemistry of pyridazines over the last decade. In particular, new examples of nucleophilic displacement of halogens, novel types of N-protection leading to a more efficient functionalization, and the introduction of C-C coupling reactions by palladium catalysts illustrate the significant development in the field. All these aspects are covered by this review.

Original languageEnglish
Pages (from-to)369-398
Number of pages30
JournalTargets in Heterocyclic Systems
Publication statusPublished - Jan 1 2002


ASJC Scopus subject areas

  • Analytical Chemistry
  • Process Chemistry and Technology
  • Organic Chemistry

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