A szkizofrénia genetikai hátterére irányuló kutatások ujabb eredményei es ezek alkalmazási lehetoségei. Irodalmi osszefoglalás.

Translated title of the contribution: Recent advances in the genetics of schizophrenia and the practical implications of the results

J. Réthelyi, Patrícia Polgár, P. Czobor, I. Bitter

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Research targeting the genetic background of schizophrenia has expanded our knowledge substantially about genes and possible pathophysiological processes playing a role in the disorder. In addition to earlier approaches, new genetic methods have been developed which offer new insight. In this review we make an attempt to summarize the findings of earlier genetic research, as well as to interpret newly emerging results that help the development of pathophysiologically oriented models of schizophrenia. We argue that besides genetic research, findings on cognitive function and of imaging studies, as well as gene-expression analyses and pharmacogenetic studies must be interpreted to reach a better understanding of the complex phenomena in schizophrenia. Synthesis of data from the different areas allows speculation about future research and practical implications.

Original languageHungarian
Pages (from-to)152-165
Number of pages14
JournalPsychiatria Hungarica : A Magyar Pszichiátriai Társaság tudományos folyóirata
Volume23
Issue number3
Publication statusPublished - 2008

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Schizophrenia
Genetic Research
Cognition
Gene Expression
Research
Genes
Genetic Background
Pharmacogenomic Testing

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

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title = "A szkizofr{\'e}nia genetikai h{\'a}tter{\'e}re ir{\'a}nyul{\'o} kutat{\'a}sok ujabb eredm{\'e}nyei es ezek alkalmaz{\'a}si lehetos{\'e}gei. Irodalmi osszefoglal{\'a}s.",
abstract = "Research targeting the genetic background of schizophrenia has expanded our knowledge substantially about genes and possible pathophysiological processes playing a role in the disorder. In addition to earlier approaches, new genetic methods have been developed which offer new insight. In this review we make an attempt to summarize the findings of earlier genetic research, as well as to interpret newly emerging results that help the development of pathophysiologically oriented models of schizophrenia. We argue that besides genetic research, findings on cognitive function and of imaging studies, as well as gene-expression analyses and pharmacogenetic studies must be interpreted to reach a better understanding of the complex phenomena in schizophrenia. Synthesis of data from the different areas allows speculation about future research and practical implications.",
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AU - Bitter, I.

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