Reactions of uridine with copper(II) acetate dimer

I. Sóvágó, R. Bruce Martin

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Two groups of cis diols may be categorized according to their reaction with the dimer Cu2(CH3COO-)4 in dimethylsulfoxide. Cis diols of the ribose class destroy the dimer, as is revealed by a shift of the visible absorption to larger wavelengths with a loss of intensity and by an increase in magnetic moment. Addition of a uridine class cis diol also results in a loss of intensity but without a shift in the characteristic dimer 715 nm absorption maximum and by little change in magnetic moment. A quantitative analysis is presented of the changes in the visible absorption intensity upon uridine addition. The dimer to monomer equilibrium of copper acetate is taken into account. One molecule of uridine as a twice deprotonated cis diolate (R) reacts with one mol of copper acetate dimer (CuA2) with expulsion of two acetates (A) as acetic acid to give Cu2A2R. A second product is also formed. Only upon inclusion of a product tetranuclear complex composed of Cu4A4R2 is there achieved a satisfactory quantitative description of the interactions over a 30 fold range of total Cu(II) concentration.

Original languageEnglish
Pages (from-to)91-96
Number of pages6
JournalInorganica Chimica Acta
Volume46
Issue numberC
DOIs
Publication statusPublished - 1980

Fingerprint

Uridine
Dimers
acetates
Acetates
dimers
Copper
copper
Magnetic moments
Ribose
Dimethyl Sulfoxide
Acetic Acid
magnetic moments
ribose
expulsion
shift
products
acetic acid
Acetic acid
quantitative analysis
monomers

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry
  • Physical and Theoretical Chemistry
  • Materials Chemistry

Cite this

Reactions of uridine with copper(II) acetate dimer. / Sóvágó, I.; Martin, R. Bruce.

In: Inorganica Chimica Acta, Vol. 46, No. C, 1980, p. 91-96.

Research output: Contribution to journalArticle

Sóvágó, I. ; Martin, R. Bruce. / Reactions of uridine with copper(II) acetate dimer. In: Inorganica Chimica Acta. 1980 ; Vol. 46, No. C. pp. 91-96.
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