Reactions of clofibric acid with oxidative and reductive radicals-Products, mechanisms, efficiency and toxic effects

Tamás Csay, Gergely Rácz, Ádám Salik, E. Takács, L. Wojnárovits

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The degradation of clofibric acid induced by hydroxyl radical, hydrated electron and O2-{bullet operator}/HO2{bullet operator} reactive species was studied in aqueous solutions. Clofibric acid was decomposed more effectively by hydroxyl radical than by hydrated electron or O2-{bullet operator}/HO2{bullet operator}. Various hydroxylated, dechlorinated and fragmentation products have been identified and quantified. A new LC-MS method was developed based on 18O isotope labeling to follow the formation of hydroxylated derivatives of clofibric acid. Possible degradation pathways have been proposed. The overall degradation was monitored by determination of sum parameters like COD, TOC and AOX. It was found that the organic chlorine degrades very effectively prior to complete mineralization. After the treatment no toxic effect was found according to Vibrio fischeri tests. However, at early stages some of the reaction products were more harmful than clofibric acid.

Original languageEnglish
Pages (from-to)72-78
Number of pages7
JournalRadiation Physics and Chemistry
Volume102
DOIs
Publication statusPublished - 2014

Fingerprint

operators
acids
hydroxyl radicals
products
degradation
crack opening displacement
reaction products
marking
chlorine
fragmentation
electrons
isotopes
aqueous solutions

Keywords

  • AOP
  • Clofibric acid
  • Ecotoxicology
  • Hydroxyl radical
  • Wastewater treatment

ASJC Scopus subject areas

  • Radiation

Cite this

Reactions of clofibric acid with oxidative and reductive radicals-Products, mechanisms, efficiency and toxic effects. / Csay, Tamás; Rácz, Gergely; Salik, Ádám; Takács, E.; Wojnárovits, L.

In: Radiation Physics and Chemistry, Vol. 102, 2014, p. 72-78.

Research output: Contribution to journalArticle

@article{343704bc0aef43d18d9ccf5240536056,
title = "Reactions of clofibric acid with oxidative and reductive radicals-Products, mechanisms, efficiency and toxic effects",
abstract = "The degradation of clofibric acid induced by hydroxyl radical, hydrated electron and O2-{bullet operator}/HO2{bullet operator} reactive species was studied in aqueous solutions. Clofibric acid was decomposed more effectively by hydroxyl radical than by hydrated electron or O2-{bullet operator}/HO2{bullet operator}. Various hydroxylated, dechlorinated and fragmentation products have been identified and quantified. A new LC-MS method was developed based on 18O isotope labeling to follow the formation of hydroxylated derivatives of clofibric acid. Possible degradation pathways have been proposed. The overall degradation was monitored by determination of sum parameters like COD, TOC and AOX. It was found that the organic chlorine degrades very effectively prior to complete mineralization. After the treatment no toxic effect was found according to Vibrio fischeri tests. However, at early stages some of the reaction products were more harmful than clofibric acid.",
keywords = "AOP, Clofibric acid, Ecotoxicology, Hydroxyl radical, Wastewater treatment",
author = "Tam{\'a}s Csay and Gergely R{\'a}cz and {\'A}d{\'a}m Salik and E. Tak{\'a}cs and L. Wojn{\'a}rovits",
year = "2014",
doi = "10.1016/j.radphyschem.2014.04.019",
language = "English",
volume = "102",
pages = "72--78",
journal = "Radiation Physics and Chemistry",
issn = "0969-806X",
publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Reactions of clofibric acid with oxidative and reductive radicals-Products, mechanisms, efficiency and toxic effects

AU - Csay, Tamás

AU - Rácz, Gergely

AU - Salik, Ádám

AU - Takács, E.

AU - Wojnárovits, L.

PY - 2014

Y1 - 2014

N2 - The degradation of clofibric acid induced by hydroxyl radical, hydrated electron and O2-{bullet operator}/HO2{bullet operator} reactive species was studied in aqueous solutions. Clofibric acid was decomposed more effectively by hydroxyl radical than by hydrated electron or O2-{bullet operator}/HO2{bullet operator}. Various hydroxylated, dechlorinated and fragmentation products have been identified and quantified. A new LC-MS method was developed based on 18O isotope labeling to follow the formation of hydroxylated derivatives of clofibric acid. Possible degradation pathways have been proposed. The overall degradation was monitored by determination of sum parameters like COD, TOC and AOX. It was found that the organic chlorine degrades very effectively prior to complete mineralization. After the treatment no toxic effect was found according to Vibrio fischeri tests. However, at early stages some of the reaction products were more harmful than clofibric acid.

AB - The degradation of clofibric acid induced by hydroxyl radical, hydrated electron and O2-{bullet operator}/HO2{bullet operator} reactive species was studied in aqueous solutions. Clofibric acid was decomposed more effectively by hydroxyl radical than by hydrated electron or O2-{bullet operator}/HO2{bullet operator}. Various hydroxylated, dechlorinated and fragmentation products have been identified and quantified. A new LC-MS method was developed based on 18O isotope labeling to follow the formation of hydroxylated derivatives of clofibric acid. Possible degradation pathways have been proposed. The overall degradation was monitored by determination of sum parameters like COD, TOC and AOX. It was found that the organic chlorine degrades very effectively prior to complete mineralization. After the treatment no toxic effect was found according to Vibrio fischeri tests. However, at early stages some of the reaction products were more harmful than clofibric acid.

KW - AOP

KW - Clofibric acid

KW - Ecotoxicology

KW - Hydroxyl radical

KW - Wastewater treatment

UR - http://www.scopus.com/inward/record.url?scp=84899840781&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84899840781&partnerID=8YFLogxK

U2 - 10.1016/j.radphyschem.2014.04.019

DO - 10.1016/j.radphyschem.2014.04.019

M3 - Article

VL - 102

SP - 72

EP - 78

JO - Radiation Physics and Chemistry

JF - Radiation Physics and Chemistry

SN - 0969-806X

ER -