Reaction of β-Bromo-β,γ-unsaturated Pyrroline Nitroxide Aldehydes and Nitriles with Aromatic N,S-Binucleophiles

Balázs Bognár, Boglárka Varga, T. Kalai, Viola Csokona, Gergely Gulyás Fekete, Cecília Sár, K. Hideg

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Reactions of β-bromo-β,γ-unsaturated pyrroline nitroxide aldehyde (1) or nitrile (4) or their diamagnetic forms (5, 6) with 2-aminothiophenol or 2-mercaptobenzimidazole were evaluated. The reaction could be reproduced more easily with the application of O-acetyl derivatives of nitroxides to generate 2-substituted-benzothiazole, pyrrolo[3,4-b]benzo[1,5]tiazepine scaffolds with 2-aminothiophenol and benzimidazo[2,1-b]pyrrolo[3,4-e]-[1,3]thiazine scaffold with 2-mercaptobenzimidazole.

Original languageEnglish
JournalJournal of Heterocyclic Chemistry
DOIs
Publication statusAccepted/In press - 2017

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Nitriles
Aldehydes
Scaffolds
Thiazines
Derivatives
2-mercaptobenzimidazole
2-aminothiophenol
pyrroline
benzothiazole

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Reaction of β-Bromo-β,γ-unsaturated Pyrroline Nitroxide Aldehydes and Nitriles with Aromatic N,S-Binucleophiles. / Bognár, Balázs; Varga, Boglárka; Kalai, T.; Csokona, Viola; Gulyás Fekete, Gergely; Sár, Cecília; Hideg, K.

In: Journal of Heterocyclic Chemistry, 2017.

Research output: Contribution to journalArticle

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AU - Kalai, T.

AU - Csokona, Viola

AU - Gulyás Fekete, Gergely

AU - Sár, Cecília

AU - Hideg, K.

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