Optically pure α‐L‐homoproline can be prepared with good yield from N‐bnezyloxycarbonyl‐L‐proline through its diazoketone‐derivative. Preparation of derivatives of α‐L‐homoproline used in peptide chemistry, and of 7‐α‐L‐homoproline‐bradykinin, as well as biological investigation of the latter are described.
ASJC Scopus subject areas
- Drug Discovery
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry