Rapid mapping of various chemicals in personal care and healthcare products by direct analysis in real time mass spectrometry

Ákos Kuki, Georgina Zelei, Lajos Nagy, Tibor Nagy, M. Zsuga, S. Kéki

Research output: Contribution to journalArticle

3 Citations (Scopus)


Residual chemicals on personal care and healthcare products, such as sanitary articles, sterile gauze bandages, nappies, plasters, were studied by direct analysis in real time mass spectrometry (DART-MS). We have identified around 40 compounds in seventeen different commercially available items. The tentative identification was further supported for about half of the chemicals by tandem mass spectrometric experiments (DART MS/MS). The most notable hazardous substances were tributyl phosphate, tris(2,4-di-tert-butylphenyl) phosphite, phthalic acid esters, erucamide, and nonylphenol ethoxylates (NPEs). In addition, we developed an efficient DART-MS analysis to determine the concentration of NPE in a swab sample. The quantitative result obtained by DART-MS was confirmed by liquid chromatography with mass spectrometric detection (LC-MS).

Original languageEnglish
Pages (from-to)241-247
Number of pages7
Publication statusPublished - Jan 15 2019



  • Direct analysis in real time (DART) tandem mass spectrometry
  • Hazardous substances
  • Nonylphenol ethoxylate (NPE)
  • Personal care and healthcare products
  • Phthalic acid ester (phthalate)
  • Semi-quantitative analysis

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry(all)
  • Biochemistry
  • Spectroscopy

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