Rapid detection of methicillin resistance in teicoplanin-resistant coagulase-negative staphylococci by a penicillin-binding protein 2′ latex agglutination method

Márta Knausz, Ágoston Ghidán, Anna Grossato, F. Rozgonyi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Thirty-five clinical isolates of coagulase-negative staphylococci with decreased glycopeptide sensitivity were examined by a penicillin-binding protein (PBP2′) latex agglutination (LA) test and were compared to the detection of the mecA gene by PCR, and oxacillin susceptibility determined minimum inhibitory concentrations. The latex test demonstrated high sensitivity and specificity for detecting methicillin resistance in coagulase-negative staphylococci after PBP2′ induction with oxacillin.

Original languageEnglish
Pages (from-to)413-416
Number of pages4
JournalJournal of Microbiological Methods
Volume60
Issue number3
DOIs
Publication statusPublished - Mar 2005

Fingerprint

Penicillin-Binding Proteins
Teicoplanin
Oxacillin
Methicillin Resistance
Coagulase
Agglutination
Latex
Staphylococcus
Latex Fixation Tests
Glycopeptides
Microbial Sensitivity Tests
Sensitivity and Specificity
Polymerase Chain Reaction
Genes

Keywords

  • Penicillin binding protein
  • Teicoplanin resistance

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Microbiology

Cite this

Rapid detection of methicillin resistance in teicoplanin-resistant coagulase-negative staphylococci by a penicillin-binding protein 2′ latex agglutination method. / Knausz, Márta; Ghidán, Ágoston; Grossato, Anna; Rozgonyi, F.

In: Journal of Microbiological Methods, Vol. 60, No. 3, 03.2005, p. 413-416.

Research output: Contribution to journalArticle

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