Antihyperglykaemiás kezelés hatékonyságát megítélő randomizált, kontrollált klinikai tanulmányok obszervációs jellegű utánkövetései

Translated title of the contribution: Randomized, controlled clinical trials with observational follow-up investigations for evaluating efficacy of antihyperglycaemic treatment

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2 Citations (Scopus)

Abstract

The effect of antihyperglycaemic (antidiabetic) treatment on the late diabetic complications is one of the most important research areas in clinical diabetology. The relationship between glycaemic control and late micro- and macrovascular complications was highlighted by the results of the DCCT (Diabetes Control and Complications Trial) with type 1 and by the UKPDS (United Kingdom Prospective Diabetes Study) with type 2 diabetic patients. In these studies, observational follow-up investigations were also performed after the close-out of the randomized phase of the trial. In addition to these landmark studies, other randomized, controlled efficacy trials were also performed with observational follow-up investigations resulting in the development of the concept of metabolic memory or metabolic legacy. In this article, the main results of the studies are summarized.

Original languageHungarian
Pages (from-to)575-582
Number of pages8
JournalOrvosi Hetilap
Volume159
Issue number15
DOIs
Publication statusPublished - Apr 1 2018

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ASJC Scopus subject areas

  • Medicine(all)

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