Radiotherapy and concurrent low-dose paclitaxel in locally advanced head and neck cancer

József Lövey, Krisztina Koronczay, E. Remenár, O. Csuka, György Németh

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

In our prospective study we examined the use of low-dose paclitaxel concurrently with radiation for patients with locally advanced head and neck cancer, who were not eligible for concurrent chemoradiation due to their poor general condition. Twenty-six patients were treated with external beam radiotherapy and received concomitantly 2 mg/m2 paclitaxel three times a week. Beside an acceptable efficacy (RR: 65%, 2-year overall survival 46%) the treatment was well tolerated and resulted in a favorable toxicity profile. This regimen is resource effective and allowed successive therapy if it was necessary and therefore may serve as an alternative for patients in poor condition with locally advanced head and neck cancer.

Original languageEnglish
Pages (from-to)171-174
Number of pages4
JournalRadiotherapy and Oncology
Volume68
Issue number2
DOIs
Publication statusPublished - Aug 2003

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Head and Neck Neoplasms
Paclitaxel
Radiotherapy
Prospective Studies
Radiation
Survival
Therapeutics

Keywords

  • Head and neck cancer
  • Irradiation
  • Paclitaxel

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Urology

Cite this

Radiotherapy and concurrent low-dose paclitaxel in locally advanced head and neck cancer. / Lövey, József; Koronczay, Krisztina; Remenár, E.; Csuka, O.; Németh, György.

In: Radiotherapy and Oncology, Vol. 68, No. 2, 08.2003, p. 171-174.

Research output: Contribution to journalArticle

Lövey, József ; Koronczay, Krisztina ; Remenár, E. ; Csuka, O. ; Németh, György. / Radiotherapy and concurrent low-dose paclitaxel in locally advanced head and neck cancer. In: Radiotherapy and Oncology. 2003 ; Vol. 68, No. 2. pp. 171-174.
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