Quantitative studies on photodynamic effects

Tamás Kriska, J. Jakus, Ágnes Keszler, L. Korecz, Dezsõ Gál

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

According to our hypothesis the interactions of triplet photosensitizer molecules with doublet free radicals generated in vivo (native free radicals) play an important role in the overall photodynamic effect (MTO mechanism). In order to support this mechanism, experiments have been performed recently in vivo, in vitro and in chemical model systems. The precondition of such studies, however, is the measurement of the kinetic parameters of various native free radicals generated in the systems investigated. Experimental results and their kinetic evaluation indicate that the triplet-doublet interactions may actually take place in the overall processes under study.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
Pages39-49
Number of pages11
Volume3191
DOIs
Publication statusPublished - 1997
EventPhotochemotherapy: Photodynamic Therapy and Other Modalities III - San Remo, Italy
Duration: Sep 4 1997Sep 4 1997

Other

OtherPhotochemotherapy: Photodynamic Therapy and Other Modalities III
CountryItaly
CitySan Remo
Period9/4/979/4/97

Fingerprint

Free Radicals
Free radicals
free radicals
Kinetics
Photosensitizer
Photosensitizing Agents
Photosensitizers
Precondition
kinetics
Interaction
Kinetic parameters
Molecules
interactions
evaluation
Evaluation
Experimental Results
Experiment
molecules
Experiments
Model

Keywords

  • ESR chemiluminescence
  • Free radical
  • Mechanism
  • Photodynamic effect
  • Singlet oxygen
  • Spin trap

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Kriska, T., Jakus, J., Keszler, Á., Korecz, L., & Gál, D. (1997). Quantitative studies on photodynamic effects. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3191, pp. 39-49) https://doi.org/10.1117/12.297817

Quantitative studies on photodynamic effects. / Kriska, Tamás; Jakus, J.; Keszler, Ágnes; Korecz, L.; Gál, Dezsõ.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3191 1997. p. 39-49.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kriska, T, Jakus, J, Keszler, Á, Korecz, L & Gál, D 1997, Quantitative studies on photodynamic effects. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 3191, pp. 39-49, Photochemotherapy: Photodynamic Therapy and Other Modalities III, San Remo, Italy, 9/4/97. https://doi.org/10.1117/12.297817
Kriska T, Jakus J, Keszler Á, Korecz L, Gál D. Quantitative studies on photodynamic effects. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3191. 1997. p. 39-49 https://doi.org/10.1117/12.297817
Kriska, Tamás ; Jakus, J. ; Keszler, Ágnes ; Korecz, L. ; Gál, Dezsõ. / Quantitative studies on photodynamic effects. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3191 1997. pp. 39-49
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