Quantitative studies on photodynamic effects

Tamás Kriska, Judit Jakus, Ágnes Keszler, László Korecz, Dezsõ Gál

Research output: Contribution to journalConference article

Abstract

According to our hypothesis the interactions of triplet photosensitizer molecules with doublet free radicals generated in vivo (native free radicals) play an important role in the overall photodynamic effect (MTO mechanism). In order to support this mechanism, experiments have been performed recently in vivo, in vitro and in chemical model systems. The precondition of such studies, however, is the measurement of the kinetic parameters of various native free radicals generated in the systems investigated. Experimental results and their kinetic evaluation indicate that the triplet-doublet interactions may actually take place in the overall processes under study.

Original languageEnglish
Pages (from-to)39-49
Number of pages11
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3191
DOIs
Publication statusPublished - Dec 1 1997
EventPhotochemotherapy: Photodynamic Therapy and Other Modalities III - San Remo, Italy
Duration: Sep 4 1997Sep 4 1997

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Keywords

  • ESR chemiluminescence
  • Free radical
  • Mechanism
  • Photodynamic effect
  • Singlet oxygen
  • Spin trap

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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