Quantitative histological studies on the hypothalamic paraventricular nucleus in rats: I. Number of cells and synaptic boutons

J. Kiss, M. Palkóvits, L. Záborszky, Eliane Tribollet, D. Szabó, G. Makara

Research output: Contribution to journalArticle

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Abstract

Quantitative histological analysis of serial sections of the adult male rat brain gives mean total estimates of the numbers of cells in the magnocellular and parvicellular divisions of the paraventricular hypothalamic nuclei (PVN) of 6600 and 11,500, respectively. The numbers and densities (number/mm3) of presynaptic bouton profiles have beeb measured and calculated on electron micrographs of the magnocellular paraventricular nucleus (mPVN). There are approximately 8 × 106 presynaptic boutons in the magnocellular subdivision: 76% of the synaptic boutons are axodendritic, 17% axosomatic and 7% are unidentified but include a few axo-axonic contacts. One third of the boutons contain dense-core vesicles although their postsynaptic contacts do not differ from other boutons. The estimated ratio of the number of boutons per neuron in the magnocellular paraventricular nucleus is 2820:1.

Original languageEnglish
Pages (from-to)217-224
Number of pages8
JournalBrain Research
Volume262
Issue number2
DOIs
Publication statusPublished - Mar 7 1983

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Paraventricular Hypothalamic Nucleus
Presynaptic Terminals
Cell Count
Secretory Vesicles
Electrons
Neurons
Brain

Keywords

  • cell density
  • electron microscopy
  • hypothalamus
  • paraventricular nucleus
  • quantitative histology
  • synaptic boutons density

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Quantitative histological studies on the hypothalamic paraventricular nucleus in rats : I. Number of cells and synaptic boutons. / Kiss, J.; Palkóvits, M.; Záborszky, L.; Tribollet, Eliane; Szabó, D.; Makara, G.

In: Brain Research, Vol. 262, No. 2, 07.03.1983, p. 217-224.

Research output: Contribution to journalArticle

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AU - Kiss, J.

AU - Palkóvits, M.

AU - Záborszky, L.

AU - Tribollet, Eliane

AU - Szabó, D.

AU - Makara, G.

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N2 - Quantitative histological analysis of serial sections of the adult male rat brain gives mean total estimates of the numbers of cells in the magnocellular and parvicellular divisions of the paraventricular hypothalamic nuclei (PVN) of 6600 and 11,500, respectively. The numbers and densities (number/mm3) of presynaptic bouton profiles have beeb measured and calculated on electron micrographs of the magnocellular paraventricular nucleus (mPVN). There are approximately 8 × 106 presynaptic boutons in the magnocellular subdivision: 76% of the synaptic boutons are axodendritic, 17% axosomatic and 7% are unidentified but include a few axo-axonic contacts. One third of the boutons contain dense-core vesicles although their postsynaptic contacts do not differ from other boutons. The estimated ratio of the number of boutons per neuron in the magnocellular paraventricular nucleus is 2820:1.

AB - Quantitative histological analysis of serial sections of the adult male rat brain gives mean total estimates of the numbers of cells in the magnocellular and parvicellular divisions of the paraventricular hypothalamic nuclei (PVN) of 6600 and 11,500, respectively. The numbers and densities (number/mm3) of presynaptic bouton profiles have beeb measured and calculated on electron micrographs of the magnocellular paraventricular nucleus (mPVN). There are approximately 8 × 106 presynaptic boutons in the magnocellular subdivision: 76% of the synaptic boutons are axodendritic, 17% axosomatic and 7% are unidentified but include a few axo-axonic contacts. One third of the boutons contain dense-core vesicles although their postsynaptic contacts do not differ from other boutons. The estimated ratio of the number of boutons per neuron in the magnocellular paraventricular nucleus is 2820:1.

KW - cell density

KW - electron microscopy

KW - hypothalamus

KW - paraventricular nucleus

KW - quantitative histology

KW - synaptic boutons density

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