Quantitative histological studies on the hypothalamic paraventricular nucleus in rats. II. Number of local and certain afferent nerve terminals

J. Kiss, M. Palkóvits, L. Záborszky, Elaine Tribollet, D. Szabó, G. Makara

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The total number and the numerical ratio of extrinsic and intrinsic (local) innervations of magnocellular neurons in the paraventricular nucleus (mPVN) were determined after surgical isolation of the nucleus in rats. Various lesions and transections of fibers running to the mPVN were performed to determine the number and possible sources of septal, hippocampal and caudal periventricular fibers to the mPVN. The relatively high proportion of possibly intrinsic connections (43%) suggests a local, integrative function of neuronal activity in the PVN. On the average, 57% of the total number of presynaptic boutons have been found to originate from outside the nucleus (extrinsic afferentation). Only 7% of these fibers ascend from caudal through the periventricular area. mPVN afferents originating from the ventral subiculum and from the lateral septal nucleus comprise about 3 and 5% of the extrinsic afferentation, respectively.

Original languageEnglish
Pages (from-to)11-20
Number of pages10
JournalBrain Research
Volume265
Issue number1
DOIs
Publication statusPublished - Apr 11 1983

Fingerprint

Paraventricular Hypothalamic Nucleus
Neurons
Septal Nuclei
Hippocampus

Keywords

  • electron microscopy
  • extrinsic/intrinsic connections
  • hypothalamus
  • paraventricular nucleus
  • quantitative histology

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Quantitative histological studies on the hypothalamic paraventricular nucleus in rats. II. Number of local and certain afferent nerve terminals. / Kiss, J.; Palkóvits, M.; Záborszky, L.; Tribollet, Elaine; Szabó, D.; Makara, G.

In: Brain Research, Vol. 265, No. 1, 11.04.1983, p. 11-20.

Research output: Contribution to journalArticle

@article{9e98786eea36460c9d45fcd622472b68,
title = "Quantitative histological studies on the hypothalamic paraventricular nucleus in rats. II. Number of local and certain afferent nerve terminals",
abstract = "The total number and the numerical ratio of extrinsic and intrinsic (local) innervations of magnocellular neurons in the paraventricular nucleus (mPVN) were determined after surgical isolation of the nucleus in rats. Various lesions and transections of fibers running to the mPVN were performed to determine the number and possible sources of septal, hippocampal and caudal periventricular fibers to the mPVN. The relatively high proportion of possibly intrinsic connections (43{\%}) suggests a local, integrative function of neuronal activity in the PVN. On the average, 57{\%} of the total number of presynaptic boutons have been found to originate from outside the nucleus (extrinsic afferentation). Only 7{\%} of these fibers ascend from caudal through the periventricular area. mPVN afferents originating from the ventral subiculum and from the lateral septal nucleus comprise about 3 and 5{\%} of the extrinsic afferentation, respectively.",
keywords = "electron microscopy, extrinsic/intrinsic connections, hypothalamus, paraventricular nucleus, quantitative histology",
author = "J. Kiss and M. Palk{\'o}vits and L. Z{\'a}borszky and Elaine Tribollet and D. Szab{\'o} and G. Makara",
year = "1983",
month = "4",
day = "11",
doi = "10.1016/0006-8993(83)91328-8",
language = "English",
volume = "265",
pages = "11--20",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Quantitative histological studies on the hypothalamic paraventricular nucleus in rats. II. Number of local and certain afferent nerve terminals

AU - Kiss, J.

AU - Palkóvits, M.

AU - Záborszky, L.

AU - Tribollet, Elaine

AU - Szabó, D.

AU - Makara, G.

PY - 1983/4/11

Y1 - 1983/4/11

N2 - The total number and the numerical ratio of extrinsic and intrinsic (local) innervations of magnocellular neurons in the paraventricular nucleus (mPVN) were determined after surgical isolation of the nucleus in rats. Various lesions and transections of fibers running to the mPVN were performed to determine the number and possible sources of septal, hippocampal and caudal periventricular fibers to the mPVN. The relatively high proportion of possibly intrinsic connections (43%) suggests a local, integrative function of neuronal activity in the PVN. On the average, 57% of the total number of presynaptic boutons have been found to originate from outside the nucleus (extrinsic afferentation). Only 7% of these fibers ascend from caudal through the periventricular area. mPVN afferents originating from the ventral subiculum and from the lateral septal nucleus comprise about 3 and 5% of the extrinsic afferentation, respectively.

AB - The total number and the numerical ratio of extrinsic and intrinsic (local) innervations of magnocellular neurons in the paraventricular nucleus (mPVN) were determined after surgical isolation of the nucleus in rats. Various lesions and transections of fibers running to the mPVN were performed to determine the number and possible sources of septal, hippocampal and caudal periventricular fibers to the mPVN. The relatively high proportion of possibly intrinsic connections (43%) suggests a local, integrative function of neuronal activity in the PVN. On the average, 57% of the total number of presynaptic boutons have been found to originate from outside the nucleus (extrinsic afferentation). Only 7% of these fibers ascend from caudal through the periventricular area. mPVN afferents originating from the ventral subiculum and from the lateral septal nucleus comprise about 3 and 5% of the extrinsic afferentation, respectively.

KW - electron microscopy

KW - extrinsic/intrinsic connections

KW - hypothalamus

KW - paraventricular nucleus

KW - quantitative histology

UR - http://www.scopus.com/inward/record.url?scp=0020597633&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020597633&partnerID=8YFLogxK

U2 - 10.1016/0006-8993(83)91328-8

DO - 10.1016/0006-8993(83)91328-8

M3 - Article

C2 - 6850311

AN - SCOPUS:0020597633

VL - 265

SP - 11

EP - 20

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1

ER -